Results 31 to 40 of about 5,038,071 (294)

Transport of proteins across mitochondrial membranes [PDF]

open access: yes, 1994
The vast majority of proteins comprising the mitochondrion are encoded by nuclear genes, synthesized on ribosomes in the cytosol, and translocated into the various mitochondrial subcompartments. During this process proteins must cross the lipid membranes
Neupert, Walter
core   +1 more source

Lipid-mediated activation of plasma membrane-localized deubiquitylating enzymes modulate endosomal trafficking

open access: yesNature Communications, 2022
The endocytic degradation of plasma membrane proteins can be modulated by deubiquitylating enzymes (DUBs). Here, the authors describe two plasma membrane localized Arabidopsis DUBs that can be activated by binding to anionic lipids and influence the ...
Karin Vogel   +10 more
doaj   +1 more source

Glycosylation can influence topogenesis of membrane proteins and reveals dynamic reorientation of nascent polypeptides within the translocon [PDF]

open access: yes, 1999
The topology of multispanning membrane proteins in the mammalian endoplasmic reticulum is thought to be dictated primarily by the first hydrophobic sequence.
Martin Spiess   +5 more
core   +1 more source

Dynamic insertion of membrane proteins at the endoplasmic reticulum [PDF]

open access: yes, 2005
Most eukaryotic membrane proteins are cotranslationally integrated into the endoplasmic reticulum membrane by the Sec61 translocation complex. They are targeted to the translocon by hydrophobic signal sequences which induce the translocation of either ...
Higy, Marie
core   +1 more source

Crystal structure of an archaeal CorB magnesium transporter

open access: yesNature Communications, 2021
CNNM/CorB proteins are a conserved family of membrane proteins associated with Mg2+ transport. Here, structures of an archaeal CorB protein in apo state and with Mg2+-ATP bound and accompanying biophysical experiments suggest direct Mg2+ transport by ...
Yu Seby Chen   +7 more
doaj   +1 more source

Deletion of Plasmodium falciparum Protein RON3 Affects the Functional Translocation of Exported Proteins and Glucose Uptake

open access: yesmBio, 2019
The survival of Plasmodium spp. within the host red blood cell (RBC) depends on the function of a membrane protein complex, termed the Plasmodium translocon of exported proteins (PTEX), that exports certain parasite proteins, collectively referred to as ...
Leanne M. Low   +9 more
doaj   +1 more source

Transport of proteins into and across the thylakoid membrane [PDF]

open access: yesJournal of Experimental Botany, 2000
The biogenesis of thylakoid proteins is a complex issue that requires the operation of at least four pathways within the chloroplast. Two of the pathways are used for soluble lumenal proteins, where the proteins bear cleavable targeting signals that are recognized by one of two distinct translocases. These pathways differ in fundamental respects.
C, Robinson, C, Woolhead, W, Edwards
openaire   +2 more sources

Studies on interactions of exported "plasmodium falciparum" membrane proteins [PDF]

open access: yes, 2014
Responsible for about 700’000 annual deaths worldwide, malaria today is still one of the major health problems in developing countries. The most deadly form of human malaria called malaria tropica is caused by the apicomplexan parasite Plasmodium ...
Dietz, Olivier
core   +1 more source

ER and vacuoles: never been closer

open access: yesFrontiers in Plant Science, 2014
The endoplasmic reticulum (ER) represents the gateway for intracellular trafficking of membrane proteins, soluble cargoes and lipids. In all eukaryotes, the best described mechanism of exiting the ER is via COPII-coated vesicles, which transport both ...
Corrado eViotti
doaj   +1 more source

Role of SEC14-like phosphatidylinositol transfer proteins in membrane identity and dynamics

open access: yesFrontiers in Plant Science, 2023
Membrane identity and dynamic processes, that act at membrane sites, provide important cues for regulating transport, signal transduction and communication across membranes.
Karolin Montag   +3 more
doaj   +1 more source

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