Results 11 to 20 of about 1,047,399 (305)

Mechanism Study of Proteins under Membrane Environment

open access: yesMembranes, 2022
Membrane proteins play crucial roles in various physiological processes, including molecule transport across membranes, cell communication, and signal transduction. Approximately 60% of known drug targets are membrane proteins.
Yue Zhang   +7 more
doaj   +1 more source

Regulation of Plasma Membrane Sterol Homeostasis by Nonvesicular Lipid Transport

open access: yesContact, 2021
Sterol contributes to the structural integrity of cellular membranes and plays an important role in the regulation of cell signaling in eukaryotes. It is either produced in the endoplasmic reticulum or taken up from the extracellular environment. In most
Dylan Hong Zheng Koh, Yasunori Saheki
doaj   +1 more source

Vesicle trafficking and vesicle fusion: mechanisms, biological functions, and their implications for potential disease therapy

open access: yesMolecular Biomedicine, 2022
Intracellular vesicle trafficking is the fundamental process to maintain the homeostasis of membrane-enclosed organelles in eukaryotic cells. These organelles transport cargo from the donor membrane to the target membrane through the cargo containing ...
Lele Cui   +9 more
doaj   +1 more source

Outer Membrane Vesicles of Acinetobacter baumannii DS002 Are Selectively Enriched with TonB-Dependent Transporters and Play a Key Role in Iron Acquisition

open access: yesMicrobiology Spectrum, 2022
Outer membrane vesicles (OMVs) of Acinetobacter baumannii DS002 carry proteins which perform selective biological functions. The proteins involved in cell wall/membrane biogenesis and inorganic ion transport and metabolism occupied a significant portion ...
Ganeshwari Dhurve   +3 more
doaj   +1 more source

Extragenic Suppression analysis of TS mutations using Sec61p [PDF]

open access: yes, 2007
During synthesis, secretory and membrane proteins are cotranslationally translocated into the lumen of the endoplasmic reticulum through an aqueous gated channel.
Sterling Smith
core   +2 more sources

Occurrence and potential mechanism of holin-mediated non-lytic protein translocation in bacteria

open access: yesMicrobial Cell, 2022
Holins are generally believed to generate large membrane lesions that permit the passage of endolysins across the cytoplasmic membrane of prokaryotes, ultimately resulting in cell wall degradation and cell lysis. However, there are more and more examples
Thomas Brüser, Denise Mehner-Breitfeld
doaj   +1 more source

Sterol transporters at membrane contact sites regulate TORC1 and TORC2 signaling. [PDF]

open access: yes, 2017
Membrane contact sites (MCSs) function to facilitate the formation of membrane domains composed of specialized lipids, proteins, and nucleic acids. In cells, membrane domains regulate membrane dynamics and biochemical and signaling pathways.
Murley, Andrew   +6 more
core   +1 more source

New putative chloroplast vesicle transport components and cargo proteins revealed using a bioinformatics approach: an Arabidopsis model. [PDF]

open access: yesPLoS ONE, 2013
Proteins and lipids are known to be transported to targeted cytosolic compartments in vesicles. A similar system in chloroplasts is suggested to transfer lipids from the inner envelope to the thylakoids. However, little is known about both possible cargo
Nadir Zaman Khan   +2 more
doaj   +1 more source

Teleological cooption of Mycobacterium tuberculosis PE/PPE proteins as porins: Role in molecular immigration and emigration

open access: yesInternational Journal of Medical Microbiology, 2021
Permeation through bacterial cells for exchange or uptake of biomolecules and ions invariably depend upon the existence of pore-forming proteins (porins) in their outer membrane. Mycobacterium tuberculosis (M.
Aquib Ehtram   +8 more
doaj   +1 more source

Transport of proteins into mitochondria [PDF]

open access: yes, 1985
Translocational intermediates of precursor proteins of ATPase F1β subunit and cytochrome c1 across mitochondrial membranes were analyzed using two different approaches, transport at low temperature and transport after binding of precursor proteins to ...
Neupert, Walter, Schleyer, Manfred
core   +1 more source

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