Results 21 to 30 of about 1,504,627 (332)

Structure and permeability of ion-channels by integrated AFM and waveguide TIRF microscopy. [PDF]

, 2014
Membrane ion channels regulate key cellular functions and their activity is dependent on their 3D structure. Atomic force microscopy (AFM) images 3D structure of membrane channels placed on a solid substrate.
Arce, Fernando Teran, Cohen, Daniel A, Lal, Ratnesh, Patel, Nirav R, Quist, Arjan P, Ramachandran, Srinivasan   +5 more
core   +2 more sources

A general method for determining secondary active transporter substrate stoichiometry

eLife, 2017
The number of ions required to drive substrate transport through a secondary active transporter determines the protein’s ability to create a substrate gradient, a feature essential to its physiological function, and places fundamental constraints on the ...
Gabriel A Fitzgerald, Christopher Mulligan, Joseph A Mindell   +2 more
doaj   +1 more source

Consensus designs and thermal stability determinants of a human glutamate transporter

eLife, 2018
Human excitatory amino acid transporters (EAATs) take up the neurotransmitter glutamate in the brain and are essential to maintain excitatory neurotransmission.
Erica Cirri, Sébastien Brier, Reda Assal, Juan Carlos Canul-Tec, Julia Chamot-Rooke, Nicolas Reyes   +5 more
doaj   +1 more source

Modulation of the ISFET response by an immunological reaction [PDF]

, 1989
A new method is presented for the detection of an immunological reaction in a membrane. Antigens (or antibodies) are taken up in a porous membrane, which covers the gate area of an ISFET. By stepwise changing of the electrolyte concentration, a transient
Bergveld, P., Bomer, J., Greve, J., Kooyman, R.P.H., Schasfoort, R.B.M.   +4 more
core   +2 more sources

Membrane Transport [PDF]

Textbook of Membrane Biology, 2018
Wardhan R, Mudgal P.
europepmc   +2 more sources

Extragenic Suppression analysis of TS mutations using Sec61p [PDF]

, 2007
During synthesis, secretory and membrane proteins are cotranslationally translocated into the lumen of the endoplasmic reticulum through an aqueous gated channel.
Sterling Smith
core   +2 more sources

The Roles of Membrane Rafts in CD32A-Mediated Phagocytosis [PDF]

, 2007
Membrane rafts are highly dynamic heterogeneous sterol- and sphingolipid-rich micro-domains on cell surfaces. They are generally believed to provide residency for cell surface molecules (e.g., adhesion and signaling molecules) and scaffolding to ...
Cheng Zhu, Periasamy Selvaraj, Timothy P. Tolentino   +2 more
core   +2 more sources

Membrane transport metabolons

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2012
In this review evidence from a wide variety of biological systems is presented for the genetic, functional, and likely physical association of membrane transporters and the enzymes that metabolize the transported substrates. This evidence supports the hypothesis that the dynamic association of transporters and enzymes creates functional membrane ...
Moraes, Trevor F., Reithmeier, Reinhart A.F.   +1 more
openaire   +2 more sources

Styrylpyridinium Derivatives as New Potent Antifungal Drugs and Fluorescence Probes

Frontiers in Microbiology, 2020
The incidence of Candida glabrata infections increases every year due to its higher resistance to commonly used antifungal drugs. We characterized the antifungal mechanism of action of eight new styrylpyridinium derivatives, with various N-alkyl chains (-
Simona Vaitkienė, Rimantas Daugelavičius, Hana Sychrová, Marie Kodedová   +3 more
doaj   +1 more source

Proton Motive Force-Dependent Hoechst 33342 Transport by the ABC Transporter LmrA of Lactococcus lactis [PDF]

, 2005
The fluorescent compound Hoechst 33342 is a substrate for many multidrug resistance (MDR) transporters and is widely used to characterize their transport activity.
Abbreviations ABC, Chen M., Doerrler W. T., Ecker G. F., Gajic O., Haugland R. P., Higuchi R., Ketchum C. J., Kuipers O. P., Lalande M. E., Lanzetta P. A., Lewinson O., Linnett P. E., Lubelski J., Lubelski J., Margolles A., Mazurkiewicz P., Orelle C., Paternostre M. T., Poelarends G. J., Putman M., Sakamoto K., Sambrook J., Shapiro A. B., Shapiro A. B., Shapiro A. B., Shapiro A. B., Sharma S., Steinfels E., Urbatsch I. L., van Veen H. W., van Veen H. W., van Veen H. W., Venter H., Viitanen P., Yu J. L.   +35 more
core   +2 more sources