Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Polyelectrolyte multilayer films as backflushable nanofiltration membranes with tunable hydrophilicity and surface charge [PDF]
A diverse set of supported polyelectrolyte multilayer (PEM) membranes with controllable surface charge, hydrophilicity, and permeability to water and salt was designed by choosing constituent polyelectrolytes and by adjusting conditions of their ...
Shan, Wenqian +6 more
core +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Fluorescence correlation spectroscopy for the characterization of membranes : A short review [PDF]
Fluorescence correlation spectroscopy (FCS) is a highly sensitive fluorescence microscopy technique that can be used to probe a wide range of biophysical processes including diffusion, Ligand-receptor binding and molecular aggregation on artificial and ...
Hwang, L.C., Thorsten Wohland
doaj
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Editorial: Artificial Membrane Transporters [PDF]
Changliang Ren +3 more
openaire +3 more sources
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Co-opted oxysterol-binding ORP and VAP proteins channel sterols to RNA virus replication sites via membrane contact sites. [PDF]
Viruses recruit cellular membranes and subvert cellular proteins involved in lipid biosynthesis to build viral replicase complexes and replication organelles.
Daniel Barajas +6 more
doaj +1 more source
National Security Commission on Artificial Intelligence: Interim Report, November 2019 [PDF]
Report presenting the National Security Commission on Artificial Intelligence's initial (NSCAI)'s preliminary assessment of artificial intelligence (AI).
National Security Commission on Artificial Intelligence (U.S.)
core
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source

