Results 71 to 80 of about 2,116,687 (302)

National Security Commission on Artificial Intelligence: Interim Report, November 2019 [PDF]

open access: yes, 2019
Report presenting the National Security Commission on Artificial Intelligence's initial (NSCAI)'s preliminary assessment of artificial intelligence (AI).
National Security Commission on Artificial Intelligence (U.S.)
core  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

Chemical cleaning of potable water membranes: A review [PDF]

open access: yes, 2010
The literature on chemical cleaning of polymeric hollow fibre ultrafiltration and microfiltration membranes used in the filtration of water for municipal water supply is reviewed. The review considers the chemical cleaning mechanism, and the perceived
Porcelli, Nicandro, Judd, Simon J.
core   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

open access: yesFEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli   +3 more
wiley   +1 more source

Membranes for Artificial Kidney

open access: yesKobunshi, 1972
人工腎に用いられる膜は,その発祥から現在に至るまで一貫してセルロース膜である。この王座は当分動きそうにない。ではいまのcuprophane膜に満足しているのかといえば,決してそうではない。透過性・強度いずれの点でも不満が多い。他の膜が提供されないから, できの悪いcuprophaneでガマンしているというのが現状である。新しい膜を開発する研究も数多く行なわれている。どれも実用化に至らないのは, 個々の点ですぐれていても総合点になるとcuprophaneより卓越したものがないからである。透過性の点はともかく, ダイアライザーという特殊構造に組み入れられたときの機械的強度に難点のあることが多い。新しい膜の中で実用化に近い点まで達しているのは,いずれも天然高分子(セルロース, コラーゲン) の膜である ...
openaire   +2 more sources

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Translocation and insertion of precursor proteins into isolated outer membranes of mitochondria [PDF]

open access: yes, 1993
Nuclear-encoded proteins destined for mitochondria must cross the outer or both outer and inner membranes to reach their final sub- mitochondrial locations. While the inner membrane can translocate preproteins by itself, it is not known whether the outer
W Neupert   +5 more
core   +2 more sources

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