Results 61 to 70 of about 313,323 (302)

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Fluctuating shells under pressure

, 2012
Thermal fluctuations strongly modify the large length-scale elastic behavior of crosslinked membranes, giving rise to scale-dependent elastic moduli. While thermal effects in flat membranes are well understood, many natural and artificial microstructures
Gompper, Gerhard, Nelson, David R., Paulose, Jayson, Vliegenthart, Gerard A.   +3 more
core   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Encoding extracellular modification of artificial cell membranes using engineered self-translocating proteins

Nature Communications
The development of artificial cells has led to fundamental insights into the functional processes of living cells while simultaneously paving the way for transformative applications in biotechnology and medicine.
Alexander Harjung, Alessandro Fracassi, Neal K. Devaraj   +2 more
doaj   +1 more source

The 'Antiretrovirals, Sexual Transmission Risk and Attitudes' (ASTRA) study. Design, methods and participant characteristics. [PDF]

, 2013
Life expectancy for people diagnosed with HIV has improved dramatically however the number of new infections in the UK remains high. Understanding patterns of sexual behaviour among people living with diagnosed HIV, and the factors associated with having
Alec Miners, Alison Rodger, Andrew N. Phillips, Andrew Speakman, Anna-Maria Geretti, Anne M. Johnson, Beatriz G. J. Grinsztejn, Ed Wilkins, , Fiona C. Lampe, Graham Hart, Jane Anderson, Jeffrey McDonnell, Jonathan Elford, Kazeem Aderogba, Lorraine Sherr, Margaret Johnson, Martin Fisher, Monica Lascar, Nicky Perry, Rebecca O’Connell, Richard Gilson, Simon Collins, Simon Edwards, William J. Burman   +23 more
core   +4 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Fluorescence correlation spectroscopy for the characterization of membranes : A short review [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2002
Fluorescence correlation spectroscopy (FCS) is a highly sensitive fluorescence microscopy technique that can be used to probe a wide range of biophysical processes including diffusion, Ligand-receptor binding and molecular aggregation on artificial and ...
Hwang, L.C., Thorsten Wohland
doaj  

A reversibly gated protein-transporting membrane channel made of DNA

Nature Communications, 2022
Artificial systems to control the transport of molecules across biomembranes can be useful for biosensing or drug delivery. Here, the authors assemble a DNA channel enabling the precisely timed, stimulus-controlled transport of functional proteins across
Swarup Dey, Adam Dorey, Leeza Abraham, Yongzheng Xing, Irene Zhang, Fei Zhang, Stefan Howorka, Hao Yan   +7 more
doaj   +1 more source

Viscous regularization and r-adaptive remeshing for finite element analysis of lipid membrane mechanics

, 2007
As two-dimensional fluid shells, lipid bilayer membranes resist bending and stretching but are unable to sustain shear stresses. This property gives membranes the ability to adopt dramatic shape changes. In this paper, a finite element model is developed
Alberts, Ayton, Bacia, Balluffi, Baumgart, Baumgart, Bozic, Božič, Byrd, Canham, Capovilla, Cirak, Cirak, Derényi, Do Carmo, Du, Du, Evans, Evans, Feng, Frey, Fygenson, Gompper, Heinrich, Heinrich, Helfrich, Ho, Hsu, Jaric, Jenkins, Jenkins, Jiang, Jülicher, Jülicher, Kawakatsu, Kraus, Lin Ma, Lipowsky, Nocedal, Noguchi, Noguchi, Powers, Seifert, Seifert, Seifert, Smith, Snapp, Sokolnikoff, Steigmann, Svetina, Svetina, Svetina, Taniguchi, Taniguchi, Toledano, Wang, Wiese, William S. Klug, Wintz, Zhu   +59 more
core   +2 more sources

Harnessing Fungal Biowelding for Constructing Mycelium‐Engineered Materials

Advanced Engineering Materials, EarlyView.
Mycelium‐bound composites (MBCs) offer low‐carbon alternatives for construction, yet interfacial bonding remains a critical challenge. This review examines fungal biowelding as a biocompatible adhesive, elucidating mycelium‐mediated interfacial mechanisms and their role in material assembly. Strategies to optimize biowelding are discussed, highlighting
Xue Brenda Bai, Xinrui Sarah Niu, Zhao Qin   +2 more
wiley   +1 more source