Results 51 to 60 of about 397,236 (254)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

A Semiconductor Under Insulator Technology in Indium Phosphide

, 2012
This Letter introduces a Semiconductor-Under-Insulator (SUI) technology in InP for designing strip waveguides that interface InP photonic crystal membrane structures.
Dalacu, Dan, Frédérick, Simon, Lapointe, Jean, Mnaymneh, Khaled, Poole, Philip J., Williams, Robin L.   +5 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Molecular engineering of chiral colloidal liquid crystals using DNA origami

, 2017
Establishing precise control over the shape and the interactions of the microscopic building blocks is essential for design of macroscopic soft materials with novel structural, optical and mechanical properties.
Dietz, Hendrik, Dogic, Zvonimir, Praetorius, Florian, Siavashpouri, Mahsa, Wachauf, Christian H., Zakhary, Mark J.   +5 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Microfabrication of palladium-silver alloy membranes for hydrogen separation [PDF]

, 2003
In this paper, a process for the microfabrication of a wafer-scale palladium-silver alloy membrane (Pd-Ag) is presented. Pd-Ag alloy films containing 23 wt% Ag were prepared by co-sputtering from pure Pd and Ag targets.
Berenschot, Johan W., de Boer, Meint J., Elwenspoek, Michael Curt, Gardeniers, Johannes G.E., Gielens, F.C. (Frank), Jansen, Henricus V., Nijdam, A.J., Nijdam, W., Tong, D.H., van Rijn, C.J.M., Wensink, H.   +10 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Безадгезивные акустические мембраны на полиимидной основе [PDF]

, 2014
Рассмотрена технология изготовления безадгезивных акустических мембран из фольгированных диэлектриков типа "алюминий—полиимид", а также их преимущества в сравнении с мембранами на лавсановой основе.Розглянуто технологію виготовлення акустичних мембран з ...
Баклаев, К.К., Воробьев, А.В., Грунянская, В.П., Жора, В.Д.   +3 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Zeolite membrane with sub-nanofluidic channels for superior blue energy harvesting

Nature Communications
Blue energy, a clean energy source derived from salinity gradients, has recently drawn increased research attention. It can be harvested using charged membranes, typically composed of amorphous materials that suffer from low power density due to their ...
Ruicong Wei, Xiaowei Liu, Li Cao, Cailing Chen, I-Chun Chen, Zhen Li, Jun Miao, Zhiping Lai   +7 more
doaj   +1 more source