Results 211 to 220 of about 992,394 (282)

Revertant Mosaicism Obscures Long‐Awaited Molecular Confirmation of Diamond‐Blackfan Anemia

American Journal of Medical Genetics Part A, EarlyView.
Nicholas A. Borja, Mustafa Tekin
wiley   +1 more source

Proinflammatory Epstein–Barr Virus Antibody Functions Track with Disease Activity in Multiple Sclerosis

Annals of Neurology, EarlyView.
Objective Epstein–Barr virus (EBV) has been implicated in the pathogenesis of multiple sclerosis (MS). Elevated immunoglobulin G (IgG) titers against EBV nuclear antigen 1 (EBNA1) represent the most consistent serological marker of MS risk, with levels remaining persistently elevated following disease onset.
Malina Behrens, Paula Terroba‐Navajas, Eline A.J. Willemse, Sabine Schädelin, Manuel Comabella, Christian Münz, Gordan Lauc, Yannic Bartsch, Jens Kuhle, Jan D. Lünemann   +9 more
wiley   +1 more source

Outcomes of concomitant <i>Pneumocystis jirovecii</i> pneumonia and cytomegalovirus co-infection in non-HIV, mechanically ventilated critically ill patients. [PDF]

Ann Med
Hung WS, Hsieh MJ, Leu SW, Hsieh MH, Fang YF, Chang PJ, Lin SM, Lin HC, Huang CC, Cheng K, Lin CY.   +10 more
europepmc   +1 more source

Nonviral Gold Nanoparticle‐Mediated Delivery of CRISPR‐Cas9 Ribonucleoprotein and Long DNA Transgenes Into Primary Blood Cells

Advanced NanoBiomed Research, EarlyView.
CRISPR/Cas9 has revolutionized the field of gene therapy, but delivery remains an outstanding issue. We propose a nonviral gold‐nanoparticle platform for co‐delivery of CRISPR/Cas9 ribonucleoprotein and long 2.1 kilobase dsDNA transgene constructs. This CRISPR‐AuNP is inexpensive to produce and mediate gene editing and DNA delivery in T cells and CD34+
Rachel A. Cunningham, Karthikeya S. V. Gottimukkala, Daniel D. Lane, Katrina Poljakov, Patricia Lipson, Mark R. Enstrom, Alessandro Rizzi, Aude G. Chapuis, Jennifer E. Adair   +8 more
wiley   +1 more source

A Phase II Trial of Olaparib plus Pembrolizumab in Patients with Recurrent Copy Number-High/p53-Abnormal Endometrial Cancer. [PDF]

Clin Cancer Res
Rubinstein MM, Ge JY, Zhou Q, Iasonos A, Weigelt B, Selenica P, Muldoon DM, Bandlamudi C, Kaczynski C, Paroder V, Higgins K, Shah P, Weissblum S, Lyn A, Liu YL, Bose S, Cohen SM, Green AK, Grisham RN, Kyi C, O'Cearbhaill RE, Tew WP, Berger MF, Aghajanian C, Makker V.   +24 more
europepmc   +1 more source

Clinicopathological Characteristics of Acute Antibody-Mediated Rejection in Pediatric Liver Transplantation-A Single-Center Study. [PDF]

J Clin Med
Szymanska S, Piątosa B, Ciopiński M, Kijewski A, Kaliciński P, Markiewicz-Kijewska M.   +5 more
europepmc   +1 more source

Feasibility and Preliminary Effectiveness of the ChulaCancer Mobile Chatbot for Supportive Care of Patients With Breast or Colorectal Cancer Receiving Chemotherapy: Pilot Randomized Controlled Trial. [PDF]

JMIR Form Res
Sompornpailin N, Susiriwatananont T, Sriuranpong V, Tanasanvimon S, Vinayanuwattikun C, Sitthideatphaiboon P, Poovorawan N, Teeyapun N, Zungsontiporn N, Pakvisal N, Panjasriprakarn P, Trakarnsanga B, Parinyanitikul N.   +12 more
europepmc   +1 more source

Enhanced Telehealth in Prostate Cancer.

JAMA Netw Open
Bange EM, Reiner AS, Liebertz C, Malling C, Kuperman G, Daly B, Chimonas S, Marcinkowski K, Doshi SD, Polubriaginof F, Stevanovic K, Murillo S, Stetson P, Schrag D, Panageas KS, Morris MJ.   +15 more
europepmc   +1 more source