Results 31 to 40 of about 75,950 (286)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Tributes & Remembrances [PDF]

open access: yes, 2005
From a memorial service held in memory of Charles Price, Professor Emeritus of Art History, at Harkness Chapel, Connecticut College, April 13, 2004. With tributes written by Barbara Zabel, Christopher London, Brian Rogers, Cynthia Willauer, Maureen ...
Deredita, Laurie M, Rogers, Brian D.
core   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Genesis and Metamorphoses of the Soviet Ritual Canon of Commemoration of the Dead Participants of the Great Patriotic War (1940s–1960s)

open access: yesИзвестия Уральского федерального университета. Серия 2: Гуманитарные науки
This article examines the emergence and subsequent development of ritual and memorial practices related to the commemoration of the dead participants in the Great Patriotic War in the USSR in the 1940s–1960s.
Aleksei Dmitrievich Popov
doaj   +1 more source

Omaeluloolisus nullindatel / Estonian Life Writing of the 2000s as a Continuity Over the Post-Soviet Period

open access: yesMethis: Studia Humaniora Estonica, 2013
A distinctive feature of the (literary) culture of the 2000s is a sudden increase in the publication of works of life writing in different genres. Although life writing as a phenomenon has received considerably more critical attention in recent years, it
Leena Kurvet-Käosaar, Rutt Hinrikus
doaj   +1 more source

2D Co‐Mo‐Hydroxide‐Based Multifunctional Material for the Development of H2‐Based Clean Energy Technologies

open access: yesAdvanced Materials, EarlyView.
2D α‐Co(OH)2 interleaved with Mo species displays an appealing dual functionality for the production and use of green hydrogen.Mo incorporation greatly benefits the electrochemical behaviour in Oxygen Evolution Reaction for H2 production, while the magnetocaloric response at liquid H2 temperature paves the way for alternative cryogenic refrigerants ...
Daniel Muñoz‐Gil   +14 more
wiley   +1 more source

Displacing the “inconvenient past”: the memory of repressions and genocides of the Soviet period in current Russia

open access: yesGenocidas ir Rezistencija
The paper provides a review of the shifts occurring in politics of memory regarding the political repressions of the Soviet period within post-Soviet Russia, spanning from the early 1990s to the present day.
Aleksey Kamenskikh
doaj   +1 more source

Reconfiguring the national canon: The Edinburgh edition of the Collected Works of Katherine Mansfield [PDF]

open access: yes, 2013
This paper looks at how the new two volume edition of the Collected Works of Katherine Mansfield, edited by Gerri Kimber and Vincent O'Sullivan, helps us to reassess the creativity of Katherine Mansfield. Gerri Kimber and Janet Wilson’s essay on the four-
Kimber, Gerri, Wilson, Janet M
core  

Christ in Glory (The Canon Brain Memorial Window)

open access: yes, 1950
Inscription: IN MEMORY OF / REV CANOR WJ BRAIN MA / FOUDNER AND FIRST RECTOR / OF THE PARIS 1907-1931. Acts 1:10-11; Shows the Ascension of Christ. The Adjacent windows show the disciples and angels as onlookers. Only window with fillet line (border), which is a double line of about 2” in width.
Williams, Yvonne, Scott, Ehtel M
openaire   +2 more sources

RETREG1‐Mediated Reticulophagy is Essential for Dendritic Cell Maturation and Function in Sepsis

open access: yesAdvanced Science, EarlyView.
Reticulophagy regulator 1 (RETREG1) maintains dendritic cell (DC) maturation and function in early sepsis. Mechanistically, activating transcription factor 6 (ATF6) acts as a direct transcription factor regulating RETREG1 expression in response to sepsis‐induced endoplasmic reticulum (ER) stress.
Ren‐Qi Yao   +28 more
wiley   +1 more source

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