Results 41 to 50 of about 75,950 (286)

Automatic tricuspid valve annulus extraction and measurement from computed tomography images

open access: yesInformatics in Medicine Unlocked
Background and objective: Tricuspid regurgitation (TR) is one of the most common forms of valvular heart diseases. The morphological information of the tricuspid valve annulus (TVA) is critical in treatment planning for TR. It is necessary to extract the
Gakuto Aoyama   +9 more
doaj   +1 more source

Dispatches from the Front: The Life of Matthew Halton, Canada’s Voice at War (Book Review) by David Halton [PDF]

open access: yes, 2017
Review of Dispatches from the Front: The Life of Matthew Halton, Canada’s Voice at War by Matthew ...
de Gara, Lisa Jane
core   +1 more source

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

open access: yesAdvanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao   +36 more
wiley   +1 more source

Anthology and Absence: The Post-9/11 Anthologizing Impulse [PDF]

open access: yes, 2015
The decade after the attacks of 9/11 and the fall of the World Trade Center saw a proliferation of New York-themed literary anthologies from a wide range of publishers.
Lovering Rounds, Anne
core   +3 more sources

Canonical Cortical Circuit Model Explains Rivalry, Intermittent Rivalry, and Rivalry Memory

open access: yesPLOS Computational Biology, 2016
It has been shown that the same canonical cortical circuit model with mutual inhibition and a fatigue process can explain perceptual rivalry and other neurophysiological responses to a range of static stimuli. However, it has been proposed that this model cannot explain responses to dynamic inputs such as found in intermittent rivalry and rivalry ...
Shashaank Vattikuti   +5 more
openaire   +4 more sources

An Artificial Antibody‐Based Toolbox Accelerates Validation of Hidden Microproteins Encoded by the Dark Genome

open access: yesAdvanced Science, EarlyView.
Microproteins are hidden treasures encoded by the “dark proteome” but remain largely underexplored due to the lack of highly efficient tools. We developed a molecularly imprinted polymers (MIPs)‐based toolbox (CLAIMID) to achieve accelerated and ultrasensitive microproteins validation at multiple biological scales (single living cells, cell populations,
Hui He   +10 more
wiley   +1 more source

DMAP1 Deficiency Suppresses Lung Cancer Progression by Destabilizing Replication Fork and Activating IFN Signaling‐Mediated Anti‐tumor Immunity

open access: yesAdvanced Science, EarlyView.
Lung cancer remains the leading cause of cancer‐related death. We investigated the role of the epigenetic regulator DMAP1 in NSCLC and found that its loss induces replication stress and DNA damage. This in turn activates type I IFN signaling via the cGAS–STING pathway and transcriptional ISG de‐repression, enhancing anti‐tumor immune responses ...
Kan Huang   +10 more
wiley   +1 more source

Custom in context : Medieval and Early Modern Scotland and England [PDF]

open access: yes, 2014
Studying custom and its context gives unique insights into relations of property, production and law in a society. The first part of the article discusses meaning in Scotland, focusing on ‘custom as normative practice, custom as unwritten law, and custom
Houston, Robert (Rab)
core   +1 more source

Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma

open access: yesAdvanced Science, EarlyView.
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian   +7 more
wiley   +1 more source

Chris van Wyk (1957–2014)

open access: yesTydskrif vir Letterkunde, 2017
The speakers at Chris van Wyk’s memorial service, held at the Johannesburg City Hall, on 9th October 2014, so aptly placed Chris and his body of poetry, short stories, memoirs and children’s stories within South Africa’s literary canon and also as a part
Terry Morris
doaj  

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