Results 111 to 120 of about 110,606 (306)

MiR‐940 Suppresses Ferroptosis by Controlling Expression of Key Regulatory Genes

Advanced Science, EarlyView.
A CRISPR‐based screening identified miR‐940 as a critical suppressor of ferroptosis in cancer. By coordinating the downregulation of pro‐ferroptotic genes with the upregulation of GPX4, miR‐940 establishes a regulatory network that protects against ferroptosis and correlates with poor clinical outcomes in distinct cancer entities.
Andrea Kolak, Juliane Tschuck, Stefanie A. I. Weiß, Daniel Kaemena, Karolin Klimm, Ana Galhoz, Larissa Ringelstetter, Myles Fennell, Juliane Merl‐Pham, Anna Artati, Stefanie Strasser, Ralph Garippa, Michael Witting, Hans Zischka, Joel A. Schick, Stefanie M. Hauck, Michael P. Menden, Michelle Vincendeau, Brent R. Stockwell, Kamyar Hadian   +19 more
wiley   +1 more source

Sociology 4120 : sociology of culture. Lecture 12. Children's drawings. Part 1

, 1984
Sociology 4120: Sociology of Culture with Prof. Clinton S. Herrick studies art, in every form, and its relationship to human society. Lecture 12: children's drawings, part 1, examines how children begin to draw shapes and then progress to more advanced ...
Memorial University of Newfoundland. Educational Television Centre; Herrick, Clinton S.
core  

mTORC2 Phosphorylation of GSDME‐N Drives Cullin4B‐Mediated Proteasomal Degradation to Suppress Pyroptosis and Confer Radioresistance in Small Cell Lung Cancer

Advanced Science, EarlyView.
Radioresistance severely limits the efficacy of therapies for small cell lung cancer (SCLC). This study reveals a novel mechanism of resistance driven by the active suppression of pyroptosis. Specifically, the mTORC2 complex directly phosphorylates GSDME‐N and promotes its CUL4B‐mediated ubiquitination and proteasomal degradation.
Qing‐qing Xu, Ci‐ming Sun, Sui‐xian Zhang, Rui Li, Chen‐fei Wu, Zai‐shan Lin, Li Li, Run‐zhe Chen, Qi‐wen Li, Yuan‐yuan Chen, Xuan Li, Ming Chen   +11 more
wiley   +1 more source

Sociology 4120 : sociology of culture. Lecture 22. Political art. Part 01

, 1984
Sociology 4120: Sociology of Culture with Prof. Clinton S. Herrick studies art, in every form, and its relationship to human society. Lecture 22: political art, part 1, examines art as a means of political persuasion, beginning with contrasting ...
Memorial University of Newfoundland. Educational Television Centre; Herrick, Clinton S.
core  

Combining Radiation‐Treated Tumor Vaccines With Mn‐MOF Nanoadjuvants to Amplify Radiation Induced Anti‐Tumor Immune Responses

Advanced Science, EarlyView.
Radiotherapy‐treated tumor membranes are integrated with Mn‐MOF nanoadjuvants to generate Mn@RM, a lymph node‐draining nanovaccine that delivers radiotherapy‐remodeled antigenic components. Mn@RM enhances dendritic cell activation, amplifies T cell‐mediated antitumor immunity, and synergizes with radiotherapy and PD‐1 blockade for combination cancer ...
Yiyu Wang, Qiqi Qi, Dezhong Li, Jingshi Tang, Weifeng Wang, Zushun Xu, Qi Xu, Fangfang Du, Qianyuan He   +8 more
wiley   +1 more source

Representing and Reconstructing Memories of the World Wars in India

RIHA Journal, 2017
This paper examines the material memorialization of the World Wars in India by looking at the India Gate, the archway located at the center of the Indian national capital, New Delhi. Although dedicated to soldiers who lost their lives in World War I, the
Jeychandran, Neelima
doaj  

Sociology 4120 : sociology of culture. Lecture 23. Political art. Part 02

, 1984
Sociology 4120: Sociology of Culture with Prof. Clinton S. Herrick studies art, in every form, and its relationship to human society. Lecture 23: political art, part 2, continues to examine art as a means of political persuasion, using more modern ...
Memorial University of Newfoundland. Educational Television Centre; Herrick, Clinton S.
core  

Epidermal METTL1‐Mediated m7G Modification Drives Psoriatic Inflammation by Stabilizing Bdkrb1 and Orchestrating Neutrophil Recruitment

Advanced Science, EarlyView.
This study unveils an unrecognized pro‐inflammatory epitranscriptomic checkpoint in psoriasis. By installing m7G modifications on the 5′ UTR of Bdkrb1 mRNA, METTL1 enhances receptor stability to orchestrate keratinocyte‐driven neutrophil recruitment via p38 MAPK signaling.
Chang Zhang, Jiayi Lu, Sihao Yan, Yirui Wang, Zhuo Li, Weiwei Chen, Yang Han, Ziyan Zhang, Yafen Yu, Qi Zhen, Liangdan Sun   +10 more
wiley   +1 more source

Sociology 4120 : sociology of culture. Lecture 26. Song structure and social structure

, 1984
Sociology 4120: Sociology of Culture with Prof. Clinton S. Herrick studies art, in every form, and its relationship to human society. Lecture 26: song structure and social structure, examining how folk songs reflect certain groups within society.Title ...
Memorial University of Newfoundland. Educational Television Centre; Herrick, Clinton S.
core  

Targeting Dnmt3a/m5C/RelA Axis Attenuates Microglia Inflammatory Response and Improves Postoperative Recovery in Chronic Compressive Cervical Spinal Cord Injury

Advanced Science, EarlyView.
A pro‐inflammatory microglial subset persists after decompression in chronic compressive cervical spinal cord injury and shows enhanced Dnmt3a‐driven m5C signaling. By stabilizing RelA mRNA, this axis sustains NF‐κB activation and postoperative neuroinflammation.
Tianyu Qin, Yuan Jiang, Yongheng Xie, Huanwei Qu, Wenbin Yan, Jingle Chen, Yining Chen, Huayi Li, Naibo Feng, Jiajun Wu, Chao Zhang, Zhengqi Huang, Ming Shi, Zhihuai Deng, Guozhi Xiao, Houqing Long   +15 more
wiley   +1 more source