CRISPR/Cas9 has revolutionized the field of gene therapy, but delivery remains an outstanding issue. We propose a nonviral gold‐nanoparticle platform for co‐delivery of CRISPR/Cas9 ribonucleoprotein and long 2.1 kilobase dsDNA transgene constructs. This CRISPR‐AuNP is inexpensive to produce and mediate gene editing and DNA delivery in T cells and CD34+
Rachel A. Cunningham +8 more
wiley +1 more source
Beyond Standard Culture: Diagnostic Value of Ureaplasma and Chlamydia in Women with UTI Symptoms. [PDF]
Avci AE +3 more
europepmc +1 more source
The inflammasome next door: characterizing pyroptosis induction in HCV-infected and uninfected bystander cells <i>in vitro</i>. [PDF]
Wallace HL +5 more
europepmc +1 more source
Communicative and Cultural Memory [PDF]
Varga, Pál S. [Hrsg.] +3 more
openaire +4 more sources
Entre merveilles et tremblements : restes du paradis dans le récit de filiation pied-noir
Melanie Koch-Fröhlich
doaj +1 more source
Characterization of cultivated nasal mucosal epithelial cell sheets for ocular surface reconstruction: an in vitro and in vivo study. [PDF]
Ma DH +8 more
europepmc +1 more source
Pubic bone osteomyelitis outcomes in patients with malignancies: a case series from an academic cancer center. [PDF]
Lewis AM +5 more
europepmc +1 more source
Nocardia Otomastoiditis in a Chemotherapy-Induced Neutropenic Patient With Diffuse Large B-cell Lymphoma: Successful Medical Management. [PDF]
Nasir I +4 more
europepmc +1 more source
Emergence of amoxicillin resistance in refractory <i>Helicobacter pylori</i> infection. [PDF]
Lin CY +11 more
europepmc +1 more source

