The Gosport War Memorial Hospital Panel report and its implications for nursing [PDF]
, 2019 Where do we even begin? How do mere words encapsulate the full horror of the Gosport War Memorial Hospital (GWMH) report (Gosport Independent Panel, 2018) and its profound implications for nursing?
Catchpole +20 more
core +2 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
THE RULE OF SÁNDOR PETŐFI IN THE MEMORY POLICY OF HUNGARIANS, SLOVAKS AND THE MEMBERS OF THE HUNGARIAN MINORITY GROUP IN SLOVAKIA IN THE LAST 150 YEARS [PDF]
, 2016 Sándor Petőfi was the greatest poet of the Hungarian romantic literature, but aft er his participation in the events of the Hungarian revolution of 1848 he became the legendary fi gure of the national liberty and republicanism.
Halász, Ivan +3 more
core +2 more sources
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Split Memory: World War I Memorialisation Practices in the Weimar Republic
Известия Уральского федерального университета. Серия 2: Гуманитарные науки, 2021 The problem of historical memory and the politics of memory, the formation and evolution of memorial culture has become relevant in the context of the “mnemonic turn” in historiography, which began in the 1980s and continues until now.
Nikolay Nikolaevich Baranov
doaj +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Usos públicos de passados ditatoriais: Visualizações na Alemanha [PDF]
, 2016 This article aims to reconstruct the visualization of the past in Germany between 1945 and 2005. The remembrances of the National Socialism shows the myriad ways in which Germans have sought to memorialize this dark part of their history.
Svampa, María Lucila
core +2 more sources
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Memorial service: A means of communication with the dead [PDF]
Glasnik Etnografskog Instituta SANU, 2005 A specific relationship toward the dead characterizes the traditional Serbian culture; this cult exists even today, in somewhat changed form. A death is always followed by the appropriate, traditional, ritual obligations that served to regulate behavior ...
Ivanović-Barišić Milina M.
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source