Results 51 to 60 of about 488,818 (300)
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Mount Rushmore: A Tomb for Dead Ideas of American Greatness [PDF]
, 2015 The Mount Rushmore National Memorial stands in the Black Hills of South Dakota as a symbol of American greatness. However, the public perceptions of the greatness represented in this memorial do not take into consideration the ideals held by the three ...
Rollins, Caleb
core +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
, 2020 Within the course of a day people perform innumerable feats of memory. They are involved in remembering when they search for their keys, find their way through a city, reminisce on episodes from their past, or join in commemorations such as independence days and religious rituals.
+5 more sources
Science Fiction Series Orville as Space for the Memorial Cultures and Memory Wars
Концепт: философия, религия, культура, 2023 The relevance of collective memory analysis comes from the increasing role of memorization in social processes, which are currently acquiring increasingly significant conflict potential.
M. W. Kyrchanoff
doaj +1 more source
Colorado 100k Lives Campaign [PDF]
, 2007 Summarizes a statewide effort to help Colorado hospitals strengthen their quality improvement systems. Includes an overview of the six interventions proven to ensure safe patient care, as well as lessons learned and success ...
core
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Hodonymy of Chengdu and Yekaterinburg: a Comparative Aspect
Научный диалог, 2020 The nominative types and models of the hodonyms of Chengdu and Yekaterinburg is compared in the article, the task of finding universals in the hodonymy is set.
E. E. Ivanova, Ling Lan
doaj +1 more source
Strategies and Resources for Integrated Community Sustainability Planning in St. Paul’s, NL [PDF]
, 2009 Under the Federal Gas Tax Agreement, Canadian municipalities are required to complete an Integrated Community Sustainability Plan (ICSP) by March, 2010.
Murphy, Ian
core +1 more source
Anthology and Absence: The Post-9/11 Anthologizing Impulse [PDF]
, 2015 The decade after the attacks of 9/11 and the fall of the World Trade Center saw a proliferation of New York-themed literary anthologies from a wide range of publishers.
Lovering Rounds, Anne
core +3 more sources