Results 51 to 60 of about 489,084 (307)
Excavaciones arqueológicas y el entorno urbano de Berlín : recordar y olvidar la huellas de la Segunda Guerra Mundial [PDF]
, 2018 This essay examines how the Second World War can be remembered through archeology at two tourism sites in Berlin. Through data collected from site visits and observations, the motifs of burial, authenticity, and historical value are found to engage ...
Florence, Eloise
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Science Fiction Series Orville as Space for the Memorial Cultures and Memory Wars
Концепт: философия, религия, культура, 2023 The relevance of collective memory analysis comes from the increasing role of memorization in social processes, which are currently acquiring increasingly significant conflict potential.
M. W. Kyrchanoff
doaj +1 more source
Strategies and Resources for Integrated Community Sustainability Planning in St. Paul’s, NL [PDF]
, 2009 Under the Federal Gas Tax Agreement, Canadian municipalities are required to complete an Integrated Community Sustainability Plan (ICSP) by March, 2010.
Murphy, Ian
core +1 more source
Trauma and Affective Spill [PDF]
, 2015 A review of Bryoni Trezise, Performing Feeling in Cultures of Memory(Palgrave Macmillan, 2014)
Willis, Emma
core +3 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
, 2017 sponsorship: ERC project acronym: DigitalMemories ERC project number: 677955, European Research Council ...
+5 more sources
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Hodonymy of Chengdu and Yekaterinburg: a Comparative Aspect
Научный диалог, 2020 The nominative types and models of the hodonyms of Chengdu and Yekaterinburg is compared in the article, the task of finding universals in the hodonymy is set.
E. E. Ivanova, Ling Lan
doaj +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source