Results 31 to 40 of about 28,144 (310)
Inclusive Heritage: Implications for the Church of England
Religions, 2023 The Church of England’s historic buildings represent the single largest group of heritage sites in the UK, playing a key public-facing role in the church’s ‘cultural witness’. However, they are complex historic environments implicated in the recent focus
Renie Chow Choy
doaj +1 more source
Memorialization as the Art of Memory: A Method to Analyse Memorials
METU Journal of Faculty of Architecture, 2010 Memorialization as the reification of past experiences crystallizes the bi-directional relation between memory and architecture in its pure form. Memorials, because of this long-established relation, constitute an expense area of knowledge where the theories of diverse -such as social, psychological, cognitive, urban or architecturalstudies intersect ...
openaire +2 more sources
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
When memory becomes heritage: Experiences from Santiago, Chile
Culture & History Digital Journal, 2014 This article explores the relationships between memory politics and urban heritage in the construction of a twenty-first century democratic society. It focuses on the case of Chile and concentrates on three examples of public buildings in the capital ...
Maria Chiara Bianchini
doaj +1 more source
First World War Memorials, Commemoration and Community in North East England, 1918-1939 [PDF]
, 2012 This thesis examines how local variations in economic, political, social, cultural and religious circumstances influenced First World War remembrance in the North East between the wars. It is divided into two parts.
COSS, DENISE
core
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Scotland's Great War Memorials [PDF]
, 2019 An overview of the process and meaning behind the memorials to the fallen of the Great War erected across Scotland c.1918-c.1939: part of a special issue of this magazine on the Great War for the centenary of ...
Penman, Michael A, Smyth, James
core