Memorials: designing for success by marrying concept and detail
Landscape Review, 2004 Memorials are archetypal. They speak of life's meaning, of value systems held in common, of significant challenges and events in the history of a tribe or nation ... They transmit universal truths and experience ... (Halprin, 1997).The only addition that
Jack Woland
doaj
When memory becomes heritage: Experiences from Santiago, Chile
Culture & History Digital Journal, 2014 This article explores the relationships between memory politics and urban heritage in the construction of a twenty-first century democratic society. It focuses on the case of Chile and concentrates on three examples of public buildings in the capital ...
Maria Chiara Bianchini
doaj +1 more source
Scottish Archaeological Research Framework: Future Thinking on Carved Stones [PDF]
, 2016 No abstract ...
Buckham, Susan +3 more
core
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Mort pour la France: conflict and commemoration in France after the First World War [PDF]
, 2000 No description ...
Edwards, Peter
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Sound, silence and the difficult heritage in the realms of remembrance: The case of Europe and Asia–Pacific region [PDF]
Muzeológia a Kultúrne DedičstvoThis article addresses the role of sound and silence in different types of memorials – monuments, memorials and museums. It shows how silence plays an important role which can be pierced by a sudden resounding sound – be it a whisper or the ringing of a ...
Olga Barbasiewicz, Marcin Zaborski
doaj +1 more source
Excavaciones arqueológicas y el entorno urbano de Berlín : recordar y olvidar la huellas de la Segunda Guerra Mundial [PDF]
, 2018 This essay examines how the Second World War can be remembered through archeology at two tourism sites in Berlin. Through data collected from site visits and observations, the motifs of burial, authenticity, and historical value are found to engage ...
Florence, Eloise
core
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source