Results 61 to 70 of about 156,426 (357)
The Importance of Beloved’s Magical Feminism in Understanding the Function of Memorials [PDF]
Akofena: Memorial architecture has gained significance in helping communities recover from collective trauma, with memory becoming a central concept in studies of traumatic events.
Yassmine BOUKHALKHAL & Djamel Eddine BELABDLI
doaj +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima +4 more
wiley +1 more source
Il Memoriale dell’Amnistia politica brasiliana: contesa simbolica e legittimità nella città delle “libertà” [PDF]
Diacronie. Studi di Storia Contemporanea, 2015 This article aims to analyze the political discourse around the implementation of the Brazilian Political Amnesty Memorial, in Belo Horizonte, state of Minas Gerais.
Priscila Cabral Almeida
doaj
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Continuing social presence of the dead: Exploring suicide bereavement through online memorialisation [PDF]
, 2014 © 2014 The Author(s). The last 10 years have seen a rise in Internet sites commemorating those lost to suicide. These sites describe the life of the deceased and the afterlife of relatives, parents, friends or siblings who have been termed the "forgotten
Bailey, Louis, Bell, Jo, Kennedy, David
core +1 more source
FEBS Open Bio, EarlyView.Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
Culture Unbound: Journal of Current Cultural Research, 2009 The pavement lies like a ledger-stone on a tomb. Buried underneath are the remains of fertile landscapes and the life they once supported. Inscribed on its upper side are epitaphic writings.
Megan Hicks
doaj +1 more source
Canada’s Peacekeepers Remember [PDF]
, 2012 Stopping wars, keeping them from restarting, and observing the implementation of cease-fires—various shades of “peacekeeping”—have always been dangerous work. It has become particularly so over the past decade as peacekeepers increasingly find themselves
Johnston, Murray
core +1 more source