Results 51 to 60 of about 2,322,321 (292)

Lived Experiences of Everyday Memory in Adults with Dyslexia: A Thematic Analysis

open access: yesBehavioral Sciences, 2023
Dyslexia-related difficulties with memory are well documented under laboratory conditions and via self-report questionnaires. However, the voice of the individual with dyslexia regarding the lived experience of memory across different memory systems and ...
James Hugo Smith-Spark, Elisa G. Lewis
doaj   +1 more source

Orienting Attention Based on Long-Term Memory Improves Perceptual Discriminations [PDF]

open access: yes, 2009
The role of attentional orienting in daily life is to selectively deploy both behavioural and neural resources towards events, based on continually changing task goals and expectations, in order to optimize performance.
Anling Rao   +3 more
core   +3 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Survival of the Fittest: Increased Stimulus Competition During Encoding Results in Fewer but More Robust Memory Traces [PDF]

open access: yes, 2019
Forgetting can be accounted for by time-indexed decay as well as competition-based interference processes. Although conventionally seen as competing theories of forgetting processes, Altmann and colleagues argued for a functional interaction between ...
Baumann, Oliver   +2 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Effects of age on long term memory for degraded speech

open access: yesFrontiers in Human Neuroscience, 2016
Prior research suggests that acoustical degradation impacts encoding of items into memory, especially in elderly subjects. We here aimed to investigate whether acoustically degraded items, that are initially encoded into memory, are more prone to ...
Christiane Thiel   +3 more
doaj   +1 more source

Turning the mind’s eye inward: the interplay between selective attention and working memory [PDF]

open access: yes, 2015
Historically, cognitive sciences have considered selective attention and working memory as largely separated cognitive functions. That is, selective attention as a concept is typically reserved for the processes that allow for the prioritization of ...
Abrahamse, Elger   +3 more
core   +2 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Short-term memory and long-term memory are still different. [PDF]

open access: yes, 2017
A commonly expressed view is that short-term memory (STM) is nothing more than activated long-term memory. If true, this would overturn a central tenet of cognitive psychology-the idea that there are functionally and neurobiologically distinct short- and
Norris, Dennis
core   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

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