Results 31 to 40 of about 5,619,365 (290)

A Robust Quantum Random Access Memory [PDF]

open access: yes, 2012
A "bucket brigade" architecture for a quantum random memory of $N=2^n$ memory cells needs $n(n+5)/2$ times of quantum manipulation on control circuit nodes per memory call.
Hong, Fang-Yu   +4 more
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Lawrence K. Williams [PDF]

open access: yes, 2005
[Excerpt] In 1952, Professor Williams graduated cum laude from Tufts University. He received his Masters Degree in 1954 from the University Illinois. In 1960, he earned a PhD in psychology from the University of Michigan. Professor Williams served in the

core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

HDAC1 modulates OGG1-initiated oxidative DNA damage repair in the aging brain and Alzheimer’s disease

open access: yesNature Communications, 2020
Defects in DNA repair have been linked to brain aging and neurodegenerative disorders. Here the authors reveal a role for HDAC1 in stimulating OGG1 activity to alleviate 8-oxoG lesions with implications in the aging brain and neurodegenerative diseases.
Ping-Chieh Pao   +17 more
doaj   +1 more source

Central limit theorems for additive functionals of ergodic Markov diffusions processes [PDF]

open access: yes, 2011
We revisit functional central limit theorems for additive functionals of ergodic Markov diffusion processes. Translated in the language of partial differential equations of evolution, they appear as diffusion limits in the asymptotic analysis of Fokker ...
Arnaud Guillin   +4 more
core   +3 more sources

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Critical Solvation Structures Arrested Active Molecules for Reversible Zn Electrochemistry

open access: yesNano-Micro Letters
Highlights Critical solvation structure changes the hydrogen bond network through “catchers”. Catcher further arrests the active molecules to promote Zn2+ deposition. The Zn||Zn symmetric battery can stably cycle for 2250 h.
Junjie Zheng   +16 more
doaj   +1 more source

Classical elliptic current algebras [PDF]

open access: yes, 2007
In this paper we discuss classical elliptic current algebras and show that there are two different choices of commutative test function algebras on a complex torus leading to two different elliptic current algebras.
Alexey Silantyev   +3 more
core   +6 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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