Results 11 to 20 of about 327,005 (268)

Social defeat drives hyperexcitation of the piriform cortex to induce learning and memory impairment but not mood-related disorders in mice

Translational Psychiatry, 2022
Clinical studies have shown that social defeat is an important cause of mood-related disorders, accompanied by learning and memory impairment in humans. The mechanism of mood-related disorders has been widely studied. However, the specific neural network
Hanjie Wang, Fang Li, Xuefeng Zheng, Lianghui Meng, Meiying Chen, Yuqing Hui, Yifei Li, Keman Xie, Jifeng Zhang, Guoqing Guo   +9 more
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Evaluation of the relationship between retinal nerve layer thickness and corpus callosum atrophy in MRI with memory impairment in patients with multiple sclerosis

Journal of Family Medicine and Primary Care, 2022
Introduction: Multiple sclerosis (MS) is a chronic neurological disease in which demyelination and loss of axons lead to disruption of communication between neurons in the central nervous system. Cognitive impairment occurs in a significant proportion of
Hamed Amirifard, Sharareh Sanei Sistani, Zahra Nezamdoust, Ehsan Haratirad, Shahram Banaie, Alireza Khosravi   +5 more
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The ubiquitin conjugating enzyme Ube2W regulates solubility of the Huntington's disease protein, huntingtin

Neurobiology of Disease, 2018
Huntington's disease (HD) is caused by a CAG repeat expansion that encodes a polyglutamine (polyQ) expansion in the HD disease protein, huntingtin (HTT). PolyQ expansion promotes misfolding and aggregation of mutant HTT (mHTT) within neurons.
Bo Wang, Li Zeng, Sean A. Merillat, Svetlana Fischer, Joseph Ochaba, Leslie M. Thompson, Sami J. Barmada, Kenneth M. Scaglione, Henry L. Paulson   +8 more
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The effect of missing data and imputation on the detection of bias in cognitive testing using differential item functioning methods

BMC Medical Research Methodology, 2022
Background Item response theory (IRT) methods for addressing differential item functioning (DIF) can detect group differences in responses to individual items (e.g., bias).
E. Nichols, J. A. Deal, B. K. Swenor, A. G. Abraham, N. M. Armstrong, K. Bandeen-Roche, M. C. Carlson, M. Griswold, F. R. Lin, T. H. Mosley, P. Y. Ramulu, N. S. Reed, A. R. Sharrett, A. L. Gross   +13 more
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Evidence for cognitive impairment in mastocytosis: prevalence, features and correlations to depression. [PDF]

PLoS ONE, 2012
Mastocytosis is a heterogeneous disease characterized by mast cells accumulation in one or more organs. We have reported that depression is frequent in mastocytosis, but although it was already described, little is known about the prevalence and features
Daniela Silva Moura, Serge Sultan, Sophie Georgin-Lavialle, Stéphane Barete, Olivier Lortholary, Raphael Gaillard, Olivier Hermine   +6 more
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Alleviating Memory Impairment through Distraction [PDF]

The Journal of Neuroscience, 2013
Distraction typically has a negative impact on memory for recent events and patients with existing memory impairment are particularly vulnerable to distractor interference. In contrast, here we establish a beneficial effect for distractor presentation in humans for both patients with memory impairment due to bilateral hippocampal lesions and healthy ...
Cashdollar, Nathan, Lavie, Nilli, Düzel, Emrah   +2 more
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POOR COGNITIVE RESERVE STATUS AS PREDICTORS OF MEMORY IMPAIRMENT AMONG ELDERLY

Malang Neurology Journal, 2023
Background: Cognitive impairment in the elderly population is commonly associated with age-associated neurodegenerative processes in the brain. The integrity of the cognitive reserve status may be an important factor that can compensate this age ...
Herpan Syafii Harahap, Yanna Indrayana
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Influence of sitting behaviors on sleep disturbance and memory impairment in breast cancer survivors

Cancer Medicine, 2020
Background The purpose was to prospectively examine the effects of sedentary behaviors on subjective memory impairment in breast cancer survivors (BCS) and the extent to which sleep disturbances mediated this pathway. Methods BCS (N = 380; Mage = 57.38 ± 
Diane K. Ehlers, Jason Fanning, Alexis Sunderlage, Joan Severson, Arthur F. Kramer, Edward McAuley   +5 more
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Circ-Vps41 positively modulates Syp and its overexpression improves memory ability in aging mice

Frontiers in Molecular Neuroscience, 2022
IntroductionAge is an established risk factor for neurodegenerative disorders. Aging-related cognitive decline is a common cause of memory impairment in aging individuals, in which hippocampal synaptic plasticity and hippocampus-dependent memory ...
Yibo Li, Hongfang Wang, Yanjing Gao, Runjiao Zhang, Qing Liu, Wenmeng Xie, Ziyu Liu, Dandan Geng, Dandan Geng, Lei Wang, Lei Wang   +10 more
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Which Neural Tract Plays a Major Role in Memory Impairment After Multiple Cerebral Infarcts? A Case Report [PDF]

Annals of Rehabilitation Medicine, 2018
Injury to the thalamocortical tract (one in the Papez circuit) that leads to memory impairment following brain injury is very rare. In this study, we present a case of partial injury to the thalamocortical tract that causes memory impairment after ...
Dae Kwon Park, Ki Hyun Byun, Dongseok Yang   +2 more
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