Results 41 to 50 of about 2,507,459 (296)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Regional Differences in Effects of APOE epsilon 4 on Cognitive Impairment in Non-Demented Subjects [PDF]

, 2011
Item does not contain fulltextBACKGROUND: The APOE epsilon4 allele is a risk factor for Alzheimer's disease (AD). APOE epsilon4 is common in non-demented subjects with cognitive impairment.
Tsolaki, M, M. Tsolaki, L. Spiru, Spiru, L., Scheltens, P., Verhey, F. R. J., Ewers, M, B. Vellas, R.W. Jones, Elias-Sonnenschein, LS, L. Frölich, Wilcock, G, Kehoe, P. G., Almkvist, O, Kehoe, P.G., Froelich, Lutz, Nobili, F, Olde Rikkert, M., Hampel, H, Verhey, F.R.J., M. Olde Rikkert, P.G. Kehoe, L. Minthon, Frisoni, GB, Elias-Sonnenschein, L.S., Lund University., Frisoni, G. B., P. Scheltens, Wahlund, L. -O., Jones, RW, Frölich, L, Spiru, L, M. Ewers, Wilcock, G., F.R.J. Verhey, Norberg, J., Froelich, L., Schelthens, P, J. Norberg, Vellas, B, Almkvist, Ove, Riqaud, AS, Almkvist, Ove,, G. Wilcock, Frolich, L., Hampel, H., L.-O. Wahlund, Lenoir, H., Norberg, Joakim,, H. Hampel, Minthon, Lennart,, L.S. Elias-Sonnenschein, Jones, R.W., O. Almkvist, F. Nobili, Soininen, H., Graff, C., Norberg, J, Rikkert, M. Olde, Olde Rikkert, M, G.B. Frisoni, NOBILI, FLAVIO MARIANO, Kehoe, PG, Vellas, B., Minthon, Lennart, Frisoni, Giovanni B., Ewers, M., Jones, R. W., Minthon, L, Frisoni, G.B., Minthon, L., Jones, Roy W., Rigaud, A. -S, Wahlund, L.O., Rigaud, A.S., Graff, Caroline, Rigaud, A. S., Visser, P.J., Lenoir, H, Visser, PJ, Wahlund, Lars-Olof, Rigaud, AS, P.J. Visser, H. Lenoir, Almkvist, O., Nobili, F., Graff, C, Frölich, Lutz, Visser, P. J., Tsolaki, M., Elias-Sonnenschein, L. S., Wahlund, L. -O, C. Graff, Wahlund, L. O., Wahlund, LO, Verhey, FR, Scheltens, P, A.-S. Rigaud, Rikkert, Marcel Olde, Soininen, H, Rigaud, A. -S., Elias Sonnenschein, L. S., H. Soininen, Rikkert, M.O., Graff, C,, Froelich, L, Almkvist, O,   +106 more
core   +1 more source

Outcomes of peripherally inserted central catheter vs conventional central venous catheters in hematological cancer patients: a systematic review and meta-analysis

Hematology
Objective This review aimed to examine if there is any difference in the risk of thrombosis and central line-associated bloodstream infection (CLABSI) with the use of peripherally inserted central catheter (PICC) and conventional central venous catheters
Weilei Ge, Chen Zheng
doaj   +1 more source

Low dose aspirin blocks breast cancer-induced cognitive impairment in mice.

PLoS ONE, 2018
Cancer patients with non-central nervous system tumors often suffer from cognitive impairment. While chemotherapy has long been attributed as the cause of these memory, learning and concentration difficulties, we recently observed cognitive impairment in
Adam K Walker, Aeson Chang, Alexandra I Ziegler, Haryana M Dhillon, Janette L Vardy, Erica K Sloan   +5 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Short-term and working memory in children with specific language impairment [PDF]

, 2006
Investigations of the cognitive processes underlying Specific Language Impairment (SLI) have implicated deficits in the storage and processing of phonological or verbal information.
Archibald, Lisa M. D.
core  

Gait characteristics in older adults using the ProtoKinetics Zeno walkway: the atherosclerosis risk in communities (ARIC) study

Frontiers in Aging Neuroscience
BackgroundGait speed is an important indicator of functional status and health outcomes in older adults. Electronic gait mats are common in research, but stopwatches are more feasible in clinical practice.
Katherine J. Hunzinger, Laura Skow, Andrea L. C. Schneider, Andrea L. C. Schneider, Michael E. Griswold, Xiaoqian Zhu, Farwa Ali, Pamela L. Lutsey, Jennifer A. Schrack, Luigi Ferrucci, Eleanor M. Simonsick, B. Gwen Windham   +11 more
doaj   +1 more source

Working Memory, Rumination, and Autobiographical Memory Specificity Impairment [PDF]

Iranian Rehabilitation Journal, 2023
Objectives: Specificity impairment is a memory alteration that occurs in people with major depressive disorder (MDD). In this investigation, we intended to shine a light on obscure aspects of executive resource and capture and rumination frameworks to ...
Pouria Rahgosha, Pezhman Hadinezhad, Seyed Hamzeh Hosseini, Ehsan Abedini   +3 more
doaj  

Verbal Memory Impairments in Dyslexia [PDF]

Archives of Clinical Neuropsychology, 2000
Although verbal memory deficits are frequently reported in reading disabled children, the specific mechanisms underlying these impairments have yet to be clearly defined. The present study used the California Verbal Learning Test-Children's Version (CVLT-C) to assess verbal learning in 57 dyslexic children and 114 controls matched for gender, age, and ...
J H, Kramer, K, Knee, D C, Delis
openaire   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source