Results 51 to 60 of about 2,827,438 (300)

Cognitive profiles of vascular and neurodegenerative MCI [PDF]

open access: yes, 2008
The objective of the thesis was to investigate the cognitive profiles of different types of mild cognitive impairment (MCI) and follow their course over time.
Nordlund, Arto
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Association of Source of Memory Complaints and Increased Risk of Cognitive Impairment and Cognitive Decline: A Community-Based Study

open access: yesChinese Medical Journal, 2018
Background: Memory complaint is common in the elderly. Recently, it was shown that self-report memory complaint was predictive of cognitive decline. This study aimed to investigate the predictive value of the source of memory complaints on the risk of ...
Xue-Mei Qi   +4 more
doaj   +1 more source

Impairment of memory for spatial context in schizophrenia. [PDF]

open access: yesNeuropsychology, 1996
A group of 33 patients with schizophrenia were compared with control participants using a spatial memory task in which words were presented on locations of a grid. In the first part of the experiment, recognition of target information (words) was tested.
Van der Linden, Martial   +4 more
openaire   +3 more sources

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Subjective memory complaints in the elderly: a sign of cognitive impairment?

open access: yesClinics
OBJECTIVES: Cognitive impairment in the elderly is frequently overlooked by general practitioners. The use of subjective memory complaints as a sign of cognitive impairment by the general practice is controversial. METHODS: Elderly individuals (N = 248)
Alessandro Ferrari Jacinto   +4 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

A Behavioural and Electrophysiological exploration of the Working Memory impairment in Developmental Dyslexia [PDF]

open access: yes, 2015
The current thesis provides a behavioural and electrophysiological exploration of Working Memory (WM) processing in developmental dyslexia. This thesis identifies a debate in the literature regarding the extent to which individuals with dyslexia have a ...
Ahmad, Jumana
core  

Low dose aspirin blocks breast cancer-induced cognitive impairment in mice.

open access: yesPLoS ONE, 2018
Cancer patients with non-central nervous system tumors often suffer from cognitive impairment. While chemotherapy has long been attributed as the cause of these memory, learning and concentration difficulties, we recently observed cognitive impairment in
Adam K Walker   +5 more
doaj   +1 more source

Animal models of memory impairment [PDF]

open access: yesPhilosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 1995
Memory impairment in the elderly resembles a mild temporal lobe dysfunction. Alterations in the hippocampal formation are also a probable basis for cognitive deficits in some animal models of ageing. For example, aged rats are impaired in hippocampal-dependent tests of spatial memory.
openaire   +3 more sources

Home - About - Disclaimer - Privacy