Results 11 to 20 of about 2,827,438 (300)

KCNQ channels regulate age-related memory impairment. [PDF]

PLoS ONE, 2013
In humans KCNQ2/3 heteromeric channels form an M-current that acts as a brake on neuronal excitability, with mutations causing a form of epilepsy. The M-current has been shown to be a key regulator of neuronal plasticity underlying associative memory and
Sonia Cavaliere, Bilal R Malik, James J L Hodge   +2 more
doaj   +2 more sources

Working memory in children with developmental disorders [PDF]

, 2009
The aim of the present study was to directly compare working memory skills across students with different developmental disorders to investigate whether the uniqueness of their diagnosis would impact memory skills.
Tracy, Alloway, Archibald, Lisa M D, Alloway, Tracy Packiam, Rajendran, Gnanathusharan, Lisa, Archibald, Archibald, Lisa M.D., Rajendran, G; id_orcid   +6 more
core   +4 more sources

CMIP and ATP2C2 Modulate Phonological Short-Term Memory in Language Impairment [PDF]

, 2009
Specific language impairment (SLI) is a common developmental disorder characterized by difficulties in language acquisition despite otherwise normal development and in the absence of any obvious explanatory factors.
Dworzynski, K., Helms, P., Dorothy V.M. Bishop, Helms, Peter J., Newbury, D., Hennessy, E, Addis, Laura, Andrea Everitt, Pickles, A, Seckl, J, Addis, L., Buckingham, Lyn-Louise, Helms, P. J., Anne O'Hare, Bishop, Dorothy V.M., Slonims, V., Emily Simonoff, Silvia Paracchini, Andrew Pickles, Slonims, Vicky, O'Hare, A, Simkin, Z, Simonoff, Emily, Duncan Shaw, Winchester, L, Pickles, A., Kindley, AD, Everitt, A., Vicky Slonims, Seckl, J. R., Bishop, DV, Clark, Ann, Gina Conti-Ramsden, Cohen, W., Buckingham, L., Conti-Ramsden, G., Hilary Cowie, Monaco, Anthony P., Seckl, J., Baird, Gillian, Cowie, Hilary, Newbury, D F, Hennessy, E., Newbury, D. F., Goodyer, Ian M., Baird, G., Katharina Dworzynski, Laura Winchester, Cohen, Wendy, Laura Addis, Buckingham, LL, Kindley, A. D., Hennessy, Elizabeth, Nasir, J., Helms, PJ, Conti-Ramsden, Gina, Bishop, D., Fisher, Simon, Paracchini, S, Goodyer, IM, Dworzynski, KD, Everitt, Andrea, Pickles, Andrew, Clark, A, Jamal Nasir, Jiannis Ragoussis, Shaw, D., Siminoff, E, Newbury, DF, Bolton, Patrick F., Lyn-Louise Buckingham, Paracchini, S., Dianne F. Newbury, Simkin, Zoe, Fisher, S. E., Anthony P. Monaco, Simkin, Z., Goodyer, I. M., Goodyer, I., Buckingham, Lyn Louise, Zoe Simkin, Miller, Laura L., O'Hare, A., Ian M. Goodyer, Ragoussis, J., Clark, A., Miller, L. L., Simonoff, Emily; id_orcid, Ragoussis, Jiannis, Wendy Cohen, Nasir, J, Ann Clark, Miller, LL, Dworzynski, Katharina, Seckl, JR, Monaco, AP, Ragoussis, Ioannis, Seckl, Jonathon R., Simon E. Fisher, Patrick F. Bolton, O'Hare, Anne, Shaw, D, Addis, L, Bishop, D. V. M., Ragoussis, J, Everitt, A, Watson, J, Peter J. Helms, Cowie, H., Cohen, W, Miller, L., Monaco, A., Paracchini, Silvia, Watson, J., Bolton, PF, Newbury, Dianne, Bolton, P. F., Buckingham, L. L., Shaw, Darren, Monaco, Anthony, Bishop, Dorothy V. M., Miller, Laura L, Jocelynne Watson, Dworzynski, K, Kindley, A. David, Kindley, A., A. David Kindley, Laura L. Miller, Baird, G, Fisher, S., Bolton, P., Fisher, SE, Conti-Ramsden, G, Cowie, H, Monaco, A. P., Slonims, V, Nasir, Jamal, Winchester, L., Bishop, DVM, Watson, Jocelynne, Newbury, Dianne F., Simonoff, E, Winchester, Laura, Jonathon R. Seckl, Gillian Baird, Simonoff, E., Fisher, Simon E., Elizabeth Hennessy, Bishop, Dorothy, Shaw, Duncan, Paracchini, Silvia; id_orcid   +150 more
core   +5 more sources

Recognition memory impairments in temporal lobe epilepsy: The contribution of recollection and metacognition [PDF]

, 2012
Temporal lobe epilepsy (TLE) is a complex neurological condition associated with a variety of memory problems. This thesis attempted to elucidate the nature and extent of memory impairments further in this clinical group by drawing on dual-process theory
Illman, Nathan Anthony
core   +5 more sources

Intervention for mixed receptive-expressive language impairment : a review [PDF]

, 2010
Children with receptive-expressive language impairment (RELI), also referred to as 'receptive language disorder' or 'mixed receptive-expressive disorder',2 form a subset of those with speech, language, and communication needs who commonly have problems ...
O'Hare, Anne E, O'Hare, A., ELSPETH MCCARTNEY, JAMES LAW, McCartney, Elspeth, Boyle, James, JAMES BOYLE, ANNE O’HARE, Law, James   +8 more
core   +4 more sources

Misaligned feeding impairs memories [PDF]

eLife, 2015
Robust sleep/wake rhythms are important for health and cognitive function. Unfortunately, many people are living in an environment where their circadian system is challenged by inappropriate meal- or work-times. Here we scheduled food access to the sleep time and examined the impact on learning and memory in mice. Under these conditions, we demonstrate
Dawn H Loh, Shekib A Jami, Richard E Flores, Danny Truong, Cristina A Ghiani, Thomas J O’Dell, Christopher S Colwell   +6 more
openaire   +5 more sources

Social defeat drives hyperexcitation of the piriform cortex to induce learning and memory impairment but not mood-related disorders in mice

Translational Psychiatry, 2022
Clinical studies have shown that social defeat is an important cause of mood-related disorders, accompanied by learning and memory impairment in humans. The mechanism of mood-related disorders has been widely studied. However, the specific neural network
Hanjie Wang, Fang Li, Xuefeng Zheng, Lianghui Meng, Meiying Chen, Yuqing Hui, Yifei Li, Keman Xie, Jifeng Zhang, Guoqing Guo   +9 more
doaj   +1 more source

The ubiquitin conjugating enzyme Ube2W regulates solubility of the Huntington's disease protein, huntingtin

Neurobiology of Disease, 2018
Huntington's disease (HD) is caused by a CAG repeat expansion that encodes a polyglutamine (polyQ) expansion in the HD disease protein, huntingtin (HTT). PolyQ expansion promotes misfolding and aggregation of mutant HTT (mHTT) within neurons.
Bo Wang, Li Zeng, Sean A. Merillat, Svetlana Fischer, Joseph Ochaba, Leslie M. Thompson, Sami J. Barmada, Kenneth M. Scaglione, Henry L. Paulson   +8 more
doaj   +1 more source

Influence of sitting behaviors on sleep disturbance and memory impairment in breast cancer survivors

Cancer Medicine, 2020
Background The purpose was to prospectively examine the effects of sedentary behaviors on subjective memory impairment in breast cancer survivors (BCS) and the extent to which sleep disturbances mediated this pathway. Methods BCS (N = 380; Mage = 57.38 ± 
Diane K. Ehlers, Jason Fanning, Alexis Sunderlage, Joan Severson, Arthur F. Kramer, Edward McAuley   +5 more
doaj   +1 more source

Diminished time-based, but undiminished event-based, prospective memory among intellectually high-functioning adults with autism: Relation to working memory ability. [PDF]

, 2013
Objective: Prospective memory (PM) is the ability to remember to carry out an intended action. Working memory is the ability to store information in mind while processing potentially distracting information.
Lind, Sophie E, Lind, Sophie E., Grainger, C., Lind, S. E., Williams, David M., Grainger, Catherine, Lind, Sophie, Williams, David, Jarrold, Christopher, Jarrold, C., Williams, D. M., Williams, David M   +11 more
core   +1 more source