Results 61 to 70 of about 3,082,752 (283)

"Oblivion is a kind of blessing": Memory Journeys in Lisa Appignanesi's The Memory Man

Caliban: French Journal of English Studies, 2018
Cet article s'intéresse aux stratégies déployées par l'écrivaine britannique Lisa Appignanesi dans son roman The Memory Man (2004) pour analyser les mécanismes littéraires qui rendent possible la représentation des processus complexes de mémoire et d ...
Silvia Pellicer-Ortín
doaj   +1 more source

Effects of alcohol on subjective ratings of prospective and everyday memory deficits [PDF]

, 2003
Background: Research has shown that heavy alcohol use has a detrimental effect on retrospective memory. Less is known about the effect of alcohol on everyday memory.
Buchanan, T., Buchanan, T., Heffernan, T.M., Heffernan, T.M., Ling, J., Ling, J., Parrott, A.C., Parrott, A.C., Rodgers, J., Rodgers, J., Scholey, A.B., Scholey, A.B.   +11 more
core   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Challenging Binaries and Unfencing Fields

Exchanges, 2019
Bryan Cheyette is Professor of Modern Literature and Culture at the University of Reading, where he directs the Identities and Minorities research group.
Rebekah Vince, Hanna Teichler
doaj   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Linking working memory and long-term memory: A computational model of the learning of new words [PDF]

, 2007
The nonword repetition (NWR) test has been shown to be a good predictor of children’s vocabulary size. NWR performance has been explained using phonological working memory, which is seen as a critical component in the learning of new words.
Baddeley A.D., Bates E., Brown G.D.A., Case R., Chi M.T.H., Conrad R., Croker S., De Groot A.D., Dunn L.M., Freudenthal D., Freudenthal D., Freudenthal D., Freudenthal D., Freudenthal D., Gathercole S.E., Gathercole S.E., Gathercole S.E., Gathercole S.E., Gathercole S.E., Gobet F., Jones G., Jones G., Jones G., Lane P.C.R., Masoura E.V., Munson B., Munson B., Nagy W.E., Page M.P.A., Papagno C., Richman H.B., Roy P., Ruchkin D.S., Schneider W., Theakston A.L., Treiman R., Zhang G.   +36 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Observations on the relationship between verbal explicit and implicit memory and neuronal density in the left and right hippocampus in temporal lobectomy patients. [PDF]

, 1998
The relationship between neuronal density and verbal memory in left and right hippocampal subfields was investigated in patients who underwent surgery for alleviation of temporal lobe epilepsy.
Beardsworth, Elizabeth, Esiri, Margaret, Zaidel, Dahlia W.   +2 more
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source