Results 41 to 50 of about 2,374,100 (265)

Age-Related Decrease in the Schaffer Collateral-Evoked EPSP in Awake, Freely, Behaving Rats

open access: yesNeural Plasticity, 2000
Synaptic response size in the CA1 region of the hippocampus in aged rats is reduced for a given stimulus intensity, compared with that elicited in young rats.
C. A. Barnes, G. Rao, G. Orr
doaj   +1 more source

Mammalian HEMK1 methylates glutamine residue of the GGQ motif of mitochondrial release factors

open access: yesScientific Reports, 2022
Despite limited reports on glutamine methylation, methylated glutamine is found to be highly conserved in a "GGQ" motif in both prokaryotes and eukaryotes. In bacteria, glutamine methylation of peptide chain release factors 1/2 (RF1/2) by the enzyme PrmC
Qi Fang   +7 more
doaj   +1 more source

Protocol for single-nucleus ATAC sequencing and bioinformatic analysis in frozen human brain tissue

open access: yesSTAR Protocols, 2022
Summary: Single-nucleus ATAC sequencing (snATAC-seq) employs a hyperactive Tn5 transposase to gain precise information about the cis-regulatory elements in specific cell types. However, the standard protocol of snATAC-seq is not optimized for all tissues,
Zechuan Shi   +4 more
doaj   +1 more source

Dual redundant core memory systems [PDF]

open access: yes, 1972
Electronic memory system consisting of series redundant drive switch circuits, triple redundant majority voted memory timing functions, and two data registers to provide functional dual redundancy is described.
Hull, F. E.
core   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Remember de Atom Egoyan. Vicis i virtuts dels sistemes de memòria

open access: yesDigithum, 2017
La extensa obra del cineasta canadiense de origen armenio Atom Egoyan se ha caracterizado por abordar, entre otros temas, las formas en que nos relacionamos con el pasado y cómo nuestra memoria se encuentra mediada por diversos tipos de tecnología en la ...
Lior Zylberman
doaj   +1 more source

Valuing and adapting appreciative inquiry to enhance well-being using a neuropsychotherapeutic framework

open access: yesSA Journal of Industrial Psychology, 2020
Orientation: Considering the impact of the unprecedented worldwide changes on employee well-being; well-being will increasingly become a competitive edge for organisations. The focus of this study was on appreciative inquiry (AI) as intervention for well-
Dirk J. Geldenhuys
doaj   +1 more source

A simple measure of memory for dynamical processes described by the generalized Langevin equation

open access: yes, 2005
Memory effects are a key feature in the description of the dynamical systems governed by the generalized Langevin equation, which presents an exact reformulation of the equation of motion.
Anatolii V. Mokshin   +10 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The brain decade in debate: I. Neurobiology of learning and memory

open access: yesBrazilian Journal of Medical and Biological Research, 2000
This article is a transcription of an electronic symposium in which some active researchers were invited by the Brazilian Society for Neuroscience and Behavior (SBNeC) to discuss the last decade's advances in neurobiology of learning and memory.
A. Baddeley   +10 more
doaj   +1 more source

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