Results 111 to 120 of about 61,156 (193)

Microsurgical clip ligation of pericallosal, anterior choroidal, and 2 middle cerebral artery aneurysms through simultaneous transsylvian and interhemispheric approaches: illustrative case. [PDF]

J Neurosurg Case Lessons
Motiwala M, Wu EM, Jones ED, Khan NR.
europepmc   +1 more source

Passenger variants as pan‐clonal markers of pediatric AML: Implications for molecular MRD

HemaSphere, Volume 10, Issue 8, August 2026.
Abstract A streamlined, sensitive, and universal molecular method for MRD detection in pediatric AML remains an unmet clinical need. Here, we propose a novel approach based on tracking somatic non‐coding passenger variants. Using whole‐genome sequencing (WGS) of diagnostic bone marrow DNA, we identify patient‐specific somatic passenger variants, which ...
Ruth Shiloh, Dana Dayan, Ifat Geron, Maor Cohen, Tamar Feuerstein, Jorge Cano‐Nistal, Nurit Gal‐Mark, Shlomit Barzilai‐Birenboim, Dafna Gaash, Michal Hameiri‐Grossman, Avraham Kahan, Jamal Mahajna, Nino Oniashvili, Hava Rosenfeld, Dan Scharf, Keren Shichrur, Elena Shinderman‐Maman, Sarah Elitzur, Yehudit Birger, Shai Izraeli, Yosef E. Maruvka   +20 more
wiley   +1 more source

Expanding the dermoscopic spectrum of Merkel cell carcinoma: A case report. [PDF]

JAAD Case Rep
Hutchinson C, Pilkinton O, Eakes J, Jones A.   +3 more
europepmc   +1 more source

Residual Al2O3 From Grit Blasted Components Operate as Third Body Wear Particles in Total Knee Arthroplasty: An Exploratory Study

Journal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 114, Issue 8, August 2026.
ABSTRACT Despite the success of total knee arthroplasty (TKA), a small percentage of devices fail. Due to the high volume of surgeries performed each year, revision total knee arthroplasty surgery presents a burden on patients and surgeons. One aspect that may improve TKA outcomes is device design, specifically the use of grit blasting to increase the ...
Peter W. Kurtz, Bradley Gordon, Charley M. Goodwin, Emma Barnes, Dinghe Liu, Steven M. Kurtz, Nicolas S. Piuzzi, William M. Mihalko, Jeremy L. Gilbert   +8 more
wiley   +1 more source

Author Correction: Commensal yeast promotes Salmonella Typhimurium virulence. [PDF]

Nature
Jaswal K, Todd OA, Flores Audelo RC, Santus W, Paul S, Duffy CM, Eshoo ET, Singh M, Miao J, Underhill DM, Peters BM, Behnsen J.   +11 more
europepmc   +1 more source

Not Missing the Notch: Detection Challenges of Juxtamembrane NOTCH1 Variant Detection in T‐Cell Acute Lymphoblastic Leukemia

Journal of Clinical Laboratory Analysis, Volume 40, Issue 15, August 2026.
ABSTRACT Background Activating mutations in NOTCH1 are frequent in T‐cell acute lymphoblastic leukemia (T‐ALL) and, in the absence of alterations in RAS or PTEN, are associated with favorable prognosis. Besides classical heterodimerization and PEST domain mutations, juxtamembrane internal tandem duplications (JME‐ITDs) represent a third class of ...
Francisco Beas, Stephan Hutter, Ferran Balbastre‐Úbeda, Sandra Novoa‐Jáuregui, Maria Gabarrós‐Subirà, Eulalia Genescà, Petri Pölönen, Torsten Haferlach, Andrés Jerez   +8 more
wiley   +1 more source

Memantine for Prevention of Cognitive Late Effects in Children and Adolescents Receiving Radiation Therapy for Brain Tumors: A Randomized, Controlled, Pilot Trial. [PDF]

Int J Radiat Oncol Biol Phys
Conklin HM, Khan RB, Ashford JM, Owens C, Simmons A, Bosley C, Hsu CW, Pan H, Gajjar A, Merchant TE.   +9 more
europepmc   +1 more source

An Open‐Label, 2‐Period, Fixed Sequence Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Single Doses of STS101 (Dihydroergotamine Nasal Powder), with and without Concomitant Itraconazole in Healthy Adult Subjects

The Journal of Clinical Pharmacology, Volume 66, Issue 8, August 2026.
Abstract Dihydroergotamine (DHE) prescribing information contains a boxed warning regarding the possibility of serious and/or life‐threatening peripheral ischemia with co‐administration of strong cytochrome P450 3A4 (CYP3A4) inhibitors. The effects of the strong CYP3A4 inhibitor itraconazole on the pharmacokinetics and safety of nasally administered ...
Detlef Albrecht, Elizabeth Hussey, Richard B. Lipton   +2 more
wiley   +1 more source

Lack of Differences in the Pharmacokinetics of Therapeutic Monoclonal Antibodies Between Japanese and Non‐Japanese Individuals

The Journal of Clinical Pharmacology, Volume 66, Issue 8, August 2026.
Abstract Evaluation of the pharmacokinetics (PK) of new drugs in Japanese individuals is regularly requested by the Japanese regulatory agency prior to participation in global clinical trials or for bridging approaches for regulatory approval. However, the need for PK assessments in the Japanese population may be less compelling for monoclonal ...
Paridhi Gupta, Ashish Sharma, Bernd Meibohm   +2 more
wiley   +1 more source

Successful autologous T cell apheresis in pediatric patients with hematologic malignancies, solid tumors, and brain tumors. [PDF]

Cytotherapy
Murphy D, Bi Y, Patel A, Li Y, Zheng Y, Poston L, Akel S, Kilpatrick C, Lockey T, Zhou S, Bertrand KC, DeRenzo C, Naik S, Sharma A, Talleur AC, Velasquez MP, Triplett BM, Gottschalk S, Selukar S, Epperly R.   +19 more
europepmc   +1 more source