Results 51 to 60 of about 224,626 (360)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Developing Microelectromechanical Systems (MEMS) [PDF]
, 2008 Intellectually and technologically, the art of design is one of the oldest forms of mankind’s expression of creativity. Since the early days of primitive man to now, humans have discovered needs that require functional artefacts to perform necessary ...
Sagoo, Jeevan
core
RF-MEMS switch actuation pulse optimization using Taguchi's method
, 2011 Copyright @ 2011 Springer-VerlagReliability and longevity comprise two of the most important concerns when designing micro-electro-mechanical-systems (MEMS) switches.
K. Tsiakmakis +7 more
core +1 more source
Impact of assembly on signal detection from thin-wall rotors of micro-gyroscopes
AIP Advances, 2014 The assembly of sealed hollow rotors, a key component in achieving liquid-levitated micro-gyroscopes, represents a significant challenge. The rotor is a thin-wall cylinder composed of materials that are only 100-μm thick.
Hai Li +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
, 2012 This paper presents the design and experimental validation of dc-dynamic biasing for \u3e50x switching time improvement in severely underdamped fringing-field electrostatic MEMS actuators.
Small, J. +4 more
core +1 more source
Bulk PZT Cantilever Based MEMS Acoustic Transducer for Cochlear Implant Applications
Proceedings, 2017 This paper presents the first acoustic experimental results of a MEMS based bulk piezoelectric transducer for use in fully implantable cochlear implants (FICI).
Aziz Koyuncuoğlu +6 more
doaj +1 more source
Micromachines, 2023 Lattice structures are a group of cellular materials composed of regular repeating unit cells. Due to their extraordinary mechanical properties, such as specific mechanical strength, ultra-low density, negative Poisson’s ratio, etc., lattice structures ...
Liu He +11 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source