Results 31 to 40 of about 27,265 (267)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Strategies for Optimizing the Morphology of CsSnI3 Perovskite Solar Cells

open access: yesCrystals, 2023
Over the past decade, organic–inorganic hybrid perovskite solar cells (PVSCs) have shown unprecedented growth in power conversion efficiency (PCE) from 3.8% to 25.7%.
Minhao Zhang   +10 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

A Point Cloud Registration Algorithm Based on Weighting Strategy for 3D Indoor Spaces

open access: yesApplied Sciences
Point cloud registration is a technology that aligns point cloud data from different viewpoints by computing coordinate transformations to integrate them into a specified coordinate system.
Wenshan Lv   +4 more
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

A High-Dynamic-Range Switched-Capacitor Sigma-Delta ADC for Digital Micromechanical Vibration Gyroscopes

open access: yesMicromachines, 2018
This paper presents a multi-stage noise shaping (MASH) switched-capacitor (SC) sigma-delta (ΣΔ) analog-to-digital converter (ADC) composed of an analog modulator with an on-chip noise cancellation logic and a reconfigurable digital decimator ...
Risheng Lv, Weiping Chen, Xiaowei Liu
doaj   +1 more source

Rotational Speed Measurement Based on LC Wireless Sensors

open access: yesSensors, 2021
This article presents a method for detecting rotational speed by LC (inductor-capacitor) wireless sensors. The sensing system consists of two identical LC resonant tanks.
Yi Zhou   +4 more
doaj   +1 more source

Off-The-Shelf MEMS for rotary MEMS [PDF]

open access: yes2012 IEEE 25th International Conference on Micro Electro Mechanical Systems (MEMS), 2012
This work demonstrates the utilization of an Off-The-Shelf (OTS) MEMS accelerometer to accurately and repeatedly determine the onset of instability and perform in situ diagnostics of a high-performance rotary MEMS device. The accelerometer is shown to provide high sensitivity, wide bandwidth vibration measurements when bonded to the stator of a MEMS ...
B. Hanrahan   +5 more
openaire   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

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