Results 31 to 40 of about 88,788 (236)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Impact of assembly on signal detection from thin-wall rotors of micro-gyroscopes

open access: yesAIP Advances, 2014
The assembly of sealed hollow rotors, a key component in achieving liquid-levitated micro-gyroscopes, represents a significant challenge. The rotor is a thin-wall cylinder composed of materials that are only 100-μm thick.
Hai Li   +3 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Bulk PZT Cantilever Based MEMS Acoustic Transducer for Cochlear Implant Applications

open access: yesProceedings, 2017
This paper presents the first acoustic experimental results of a MEMS based bulk piezoelectric transducer for use in fully implantable cochlear implants (FICI).
Aziz Koyuncuoğlu   +6 more
doaj   +1 more source

Semiparametric Vector MEM [PDF]

open access: yesSSRN Electronic Journal, 2008
SUMMARYFinancial time series are often non‐negative‐valued (volumes, trades, durations, realized volatility, daily range) and exhibit clustering. When joint dynamics is of interest, the vector multiplicative error model (vMEM; the element‐by‐element product of a vector of conditionally autoregressive scale factors and a multivariate i.i.d.
CIPOLLINI, FABRIZIO   +2 more
openaire   +3 more sources

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Smart Lattice Structures with Self-Sensing Functionalities via Hybrid Additive Manufacturing Technology

open access: yesMicromachines, 2023
Lattice structures are a group of cellular materials composed of regular repeating unit cells. Due to their extraordinary mechanical properties, such as specific mechanical strength, ultra-low density, negative Poisson’s ratio, etc., lattice structures ...
Liu He   +11 more
doaj   +1 more source

Off-The-Shelf MEMS for rotary MEMS [PDF]

open access: yes2012 IEEE 25th International Conference on Micro Electro Mechanical Systems (MEMS), 2012
This work demonstrates the utilization of an Off-The-Shelf (OTS) MEMS accelerometer to accurately and repeatedly determine the onset of instability and perform in situ diagnostics of a high-performance rotary MEMS device. The accelerometer is shown to provide high sensitivity, wide bandwidth vibration measurements when bonded to the stator of a MEMS ...
B. Hanrahan   +5 more
openaire   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Strategies for Optimizing the Morphology of CsSnI3 Perovskite Solar Cells

open access: yesCrystals, 2023
Over the past decade, organic–inorganic hybrid perovskite solar cells (PVSCs) have shown unprecedented growth in power conversion efficiency (PCE) from 3.8% to 25.7%.
Minhao Zhang   +10 more
doaj   +1 more source

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