Results 51 to 60 of about 7,870,713 (201)

Single-cell RNA sequencing and in vitro validation reveal risankizumab induces anti-inflammatory macrophage polarization in psoriasis

open access: yesEuropean Journal of Medical Research
Background Risankizumab was an approved novel drug by Japan for psoriasis, we aimed to explore its underlying therapeutic mechanism through the single-cell RNA sequencing (scRNA-seq) technology.
Yuan Yuan   +7 more
doaj   +1 more source

Targeted Regulation of HSP70 by the ARP2/3 Complex in Mammary Epithelial Cells and Its Impact on Host Cell Apoptosis

open access: yesBiomolecules
Mastitis is frequently triggered by the bacterial disruption of the epithelial cell barrier. The actin-related protein 2/3 complex (Arp2/3), a major endogenous protein involved in cytoskeletal regulation, plays a crucial role in preserving epithelial ...
Tingji Yang   +11 more
doaj   +1 more source

The Significance of Fibrosis Quantification as a Marker in Assessing Pseudo-Capsule Status and Clear Cell Renal Cell Carcinoma Prognosis

open access: yesDiagnostics, 2020
Fibrosis plays an important role in tumor growth and progression, and thus, we aimed to determine whether renal fibrosis is correlated with the clinical and pathological characteristics and prognosis of clear cell renal cell carcinoma (ccRCC).
Caipeng Qin   +5 more
doaj   +1 more source

Men's Perceptions of Non‐Cancer Related Lymphoedema: A Qualitative Diary Study

open access: yesNursing &Health Sciences, Volume 27, Issue 3, September 2025.
ABSTRACT Lymphoedema is a chronic condition caused by lymphatic dysfunction, resulting in persistent swelling. Although men are significantly affected, their experiences, particularly regarding masculine identity, remain underexplored. This UK‐based study examined how men live with non‐cancer‐related lymphoedema, drawing on hegemonic masculinity and ...
Garry Cooper   +3 more
wiley   +1 more source

A role for curcumin in preventing liver fibrosis in animals: a systematic review and meta-analysis

open access: yesFrontiers in Pharmacology
ObjectiveThis meta-analysis aimed to determine the efficacy of curcumin in preventing liver fibrosis in animal models.MethodsA systematic search was conducted on studies published from establishment to November 2023 in PubMed, Web of Science, Embase ...
Bo-Hao Huang   +6 more
doaj   +1 more source

Exploring the Challenges of Context in Accessing Mental Health Support in Rural New Zealand: A Case Study Approach

open access: yesJournal of Advanced Nursing, Volume 81, Issue 7, Page 4038-4051, July 2025.
ABSTRACT Objective This paper explores the complexities that impact access to mental health services in rural New Zealand. Historical, cultural, social and political factors will be examined against the philosophical positioning of Foucault and Fairclough.
Philip Ferris‐Day   +3 more
wiley   +1 more source

A real-world pharmacovigilance study of FDA adverse event reporting system events for diazepam

open access: yesFrontiers in Pharmacology
Background: Diazepam, one of the benzodiazepines, is widely used clinically to treat anxiety, for termination of epilepsy, and for sedation. However, the reports of its adverse events (AEs) have been numerous, and even fatal complications have been ...
Weizhen He, Yang Wang, Kaiqin Chen
doaj   +1 more source

Loose Women, Lecherous Men [PDF]

open access: yes, 1999
A review of Loose Women, Lecherous Men, by Linda ...
Soble, Alan
core   +1 more source

Knowledge of HIV status among men aged 20–35 years in Lusaka, Zambia: Findings from a pilot time location sampling survey in the “Yaba Guy Che” (for the guys) study

open access: yesTropical Medicine &International Health, Volume 30, Issue 7, Page 712-720, July 2025.
Abstract Objectives We conducted a pilot time location sampling survey with young men aged 20–35 years in Lusaka, Zambia and aimed to describe knowledge of HIV status and determine factors associated with knowledge of HIV status. Methods Hotspots where men congregate were identified in a densely populated community in Lusaka. Hotspots were grouped into
Mwelwa Muleba Phiri   +10 more
wiley   +1 more source

Advances in Prognostic Value of Peripheral Blood Inflammatory Indexes in Non-small Cell Lung Cancer

open access: yesZhongliu Fangzhi Yanjiu, 2019
Lung cancer is a kind of malignant tumor with high morbidity and poor prognosis, and non-small cell lung cancer is in the majority. Some indications other than anatomical changes, can be helpful for monitoring disease progress.
LI Bingxue, FAN Huiting, LIN Hongsheng
doaj   +1 more source

Home - About - Disclaimer - Privacy