Results 51 to 60 of about 3,068,884 (234)

Single-cell RNA sequencing and in vitro validation reveal risankizumab induces anti-inflammatory macrophage polarization in psoriasis

European Journal of Medical Research
Background Risankizumab was an approved novel drug by Japan for psoriasis, we aimed to explore its underlying therapeutic mechanism through the single-cell RNA sequencing (scRNA-seq) technology.
Yuan Yuan, Linzi Li, Lihong Yang, Jiyuan Zheng, Guang Gao, Ting Tan, Jing Liu, Wen Sun   +7 more
doaj   +1 more source

Gut Microbiota-Dependent Marker TMAO in Promoting Cardiovascular Disease: Inflammation Mechanism, Clinical Prognostic, and Potential as a Therapeutic Target

Frontiers in Pharmacology, 2019
Cardiovascular disease (CVD) is the leading cause of death worldwide, especially in developed countries, and atherosclerosis (AS) is the common pathological basis of many cardiovascular diseases (CVDs) such as coronary heart disease (CHD).
Shengjie Yang, Xinye Li, Xinye Li, Fan Yang, Ran Zhao, Ran Zhao, Xiandu Pan, Xiandu Pan, Jiaqi Liang, Li Tian, Xiaoya Li, Xiaoya Li, Longtao Liu, Yanwei Xing, Min Wu   +14 more
doaj   +1 more source

Reflections on Using the Eating Disorders Examination to Assess Eating Disorder Pathology in Queer Men

International Journal of Eating Disorders, Volume 58, Issue 11, Page 2157-2166, November 2025.
ABSTRACT Objective Queer men face potent appearance‐related pressures that exacerbate their eating disorder risk. While the Eating Disorder Examination (EDE) is a widely used eating disorder assessment, queer men may experience unique motivations for disordered eating that may impact its administration in this population. To generate practical guidance
Emma Austen, Jocelyn R. Clarke, Isabel Chua, Sarah Giles, Patrick Haylock, Imran M. Keshani, Po‐Han Kung, Elyse O’Loghlen, Scott Griffiths   +8 more
wiley   +1 more source

Targeted Regulation of HSP70 by the ARP2/3 Complex in Mammary Epithelial Cells and Its Impact on Host Cell Apoptosis

Biomolecules
Mastitis is frequently triggered by the bacterial disruption of the epithelial cell barrier. The actin-related protein 2/3 complex (Arp2/3), a major endogenous protein involved in cytoskeletal regulation, plays a crucial role in preserving epithelial ...
Tingji Yang, Bo Fang, Yan Chen, Dan Bao, Jiang Zhang, Peiwen Liu, Zhiwei Duan, Yuxuan He, Xingxu Zhao, Quan-Wei Zhang, Wei-Tao Dong, Yong Zhang   +11 more
doaj   +1 more source

The Six Thinking Hats and Their Effect on Improving the Skill of Lesson Planning and attitudes of Students in Teaching Practicum within the Faculty of Physical Education for Men [PDF]

International Journal of Sports Science and Arts, 2016
Study Importance 1- Shedding light on one of teaching strategies (Six Thinking-Hats) and trying to practically apply it on Field Practicum syllabus, 2- Helping students with low and mid-level to access to good performance level of planning Physical ...
Ahmed Mohamed Allam, Walid ElMesawy
doaj   +1 more source

Of mice and men [PDF]

BMJ Case Reports, 2014
A case study of a patient returning from sub-Saharan Africa with a febrile illness and symptoms reminiscent of a previous malarial infection is discussed. The patient had a relative bradycardia with respect to febrile episodes, a transient macular rash and thrombocytopenia.
Andrew, D'Silva, Rebecca, Akroyd, Tim, Brooks, Umesh, Dashora   +3 more
openaire   +2 more sources

Understanding Loneliness as a Preventive Health Priority Among Men: Findings From an Australian Population Survey

Health Promotion Journal of Australia, Volume 36, Issue 4, October 2025.
ABSTRACT Issue Addressed Masculinity norms and risky behaviours are often identified as drivers of poorer health among men, and one underlying factor that is increasingly found to be important is loneliness. The aim of this study is to describe the prevalence of loneliness in Australian men and its relationship with preventive health capabilities ...
Michelle H. Lim, Nicole Halim, Robert Palmer, Tim J. Moss, Simon von Saldern, Bernie Marshall, Ben J. Smith   +6 more
wiley   +1 more source

Optical analysis of RE3+ (RE = Pr, Tm): MgLa2V2O9 phosphors

Discover Materials
This paper reports on the synthesis of RE3+ (RE = Pr, Tm): MgLa2V2O9 powder phosphors using the conventional solid-state reaction method. XRD analysis confirms the monoclinic crystalline nature of the synthesized phosphors.
S. Hajira, P. Aruna, C. Balanarayana, B. Sudhakar Reddy   +3 more
doaj   +1 more source

The Effects of Glucose Fluctuation on the Severity of Coronary Artery Disease in Type 2 Diabetes Mellitus

Journal of Diabetes Research, 2013
Objectives. To explore the difference of glucose fluctuations between the normal subjects and diabetes mellitus (DM) patients and explore their impact on the development of CAD in type 2 DM patients. Methods.
Xingguang Zhang, Xiuping Xu, Xiumin Jiao, Jinxiao Wu, Shujing Zhou, Xiaofeng Lv   +5 more
doaj   +1 more source

The Impact of Metformin on Plasma Prolactin Levels in Antipsychotics‐Treated Men With Hyperprolactinemia and Early‐Onset Androgenic Alopecia

Clinical Endocrinology, Volume 103, Issue 4, Page 513-522, October 2025.
ABSTRACT Objective Metformin decreases elevated levels of pituitary hormones. Little is known about the association between the reproductive axis and hormonal effects of this drug. The purpose of our study was to investigate whether activity of the hypothalamic‐pituitary‐gonadal axis determines metformin action on prolactin levels in men with prolactin
Robert Krysiak, Karolina Kowalcze, Marek Krzystanek, Witold Szkróbka, Bogusław Okopień   +4 more
wiley   +1 more source