Results 91 to 100 of about 3,490 (181)

Prophylactic thyroidectomy in children with multiple endocrine neoplasia type 2 [PDF]

, 2018
Background In patients with multiple endocrine neoplasia type 2 (MEN2) syndrome, genetic testing offers early diagnosis, stratifies the risk of developing medullary thyroid cancer (MTC) and informs the timing of thyroidectomy. The efficacy of treatment,
Prete, FP, MEN2 in Children UK Collaborative Group, Kurzawinski, TR, Morkane, C, Brain, C, Abdel-Aziz, T   +5 more
core   +1 more source

RET-mediated modulation of tumor microenvironment and immune response in multiple endocrine neoplasia type 2 (MEN2).

, 2018
Medullary thyroid carcinomas (MTC) arise from thyroid parafollicular, calcitonin-producing C-cells and can occur either as sporadic or as hereditary diseases in the context of familial syndromes, including multiple endocrine neoplasia 2A (MEN2A ...
Castellone MD, Melillo RM
core   +2 more sources

Genetic diagnosis of endocrine disorders in Cyprus through the Cyprus Institute of Neurology and Genetics: an ENDO-ERN Reference Center

Orphanet Journal of Rare Diseases
The report covers the current and past activities of the department Molecular Genetics-Function and Therapy (MGFT) at the Cyprus Institute of Neurology and Genetics (CING), an affiliated Reference Center for the European Reference Network on Rare ...
Vassos Neocleous, Pavlos Fanis, Meropi Toumba, Nicos Skordis, Leonidas A. Phylactou   +4 more
doaj   +1 more source

Challenges in molecular diagnosis of multiple endocrine neoplasia

Frontiers in Endocrinology
Multiple endocrine neoplasia (MEN) is a group of rare genetic diseases characterized by the occurrence of multiple tumors of the endocrine system in the same patient. The first MEN described was MEN1, followed by MEN2A, and MEN2B.
Pauline Romanet, Théo Charnay, Nicolas Sahakian, Thomas Cuny, Frédéric Castinetti, Anne Barlier   +5 more
doaj   +1 more source

Neoplasias endocrinas múltiples: de lo molecular a lo clínico

Revista Médica Clínica Las Condes
Resumen: Las neoplasias endocrinas múltiples (NEM) tipo 1, 2 (se subdivide en 2A y 2B), 4 y 5; constituyen síndromes genéticos hereditarios con un patrón de transmisión autosómico dominante.
Nelson Wohllk, MD, Consuelo Olave, MD
doaj   +1 more source

Consensus: Guidelines for diagnosis and therapy of MEN type 1 and type 2

, 2001
This is a consensus statement from an international group, mostly of clinical endocrinologists. MEN1 and MEN2 are hereditary cancer syndromes. The commonest tumors secrete PTH or gastrin in MEN1, and calcitonin or catecholamines in MEN2.
Mannelli, M, Pacini, F, Thakker, RV, Bilezikian, JP, Gheri, RG, Falchetti, A, Conte-Devolx, B, Tonelli, F, Thakker, Rajesh, Angeli, A, Brandi, ML, Tamburrano, G, Beck-Peccoz, P, Libroia, A, Skogseid, B, Wells, SA, Marx, SJ, Lips, CJM, Lombardi, G, Tomassetti, P, Ponder, BA, Gagel, RF, Ponder, BAJ, Lips, CJ, Raue, F, Thompson, NW, Wells S A, J, Bordi, C   +27 more
core   +1 more source

Impact of Incretin Mimetics on Thyroid Cancer Among Patients with Type 2 Diabetes: A Retrospective Cohort Time-to-Event Analysis

Pharmacoepidemiology
Background: Incretin mimetics, including glucagon-like peptide-1 receptor agonists (GLP-1 receptor agonist) and dipeptidyl peptidase-4 (DPP-4) inhibitors, have been increasingly utilized for glycemic control in patients with type 2 diabetes (T2D ...
Michael W. Strand, Daniel Chow, Weining Shen, Jonathan H. Watanabe   +3 more
doaj   +1 more source

Thyroid Malignancy and Cutaneous Lichen Amyloidosis: Key Points Amid RET Pathogenic Variants in Medullary Thyroid Cancer/Multiple Endocrine Neoplasia Type 2 (MEN2)

We aimed to provide an updated narrative review with respect to the RET pathogenic variants and their implications at the clinical and molecular level in the diagnosis of medullary thyroid cancer (MTC)/multiple endocrine neoplasia (MEN) type 2 ...
Adrian Ciuche, Laura-Semonia Stanescu, Mara Carsote, Andreea-Maria Radu, Mihai-Lucian Ciobica, Adina Ghemigian, Claudiu Nistor, Florica Sandru   +7 more
core   +1 more source

Prophylactic thyroidectomy in children with multiple endocrine neoplasia type 2

Background - In patients with multiple endocrine neoplasia type 2 (MEN2) syndrome, genetic testing offers early diagnosis, stratifies the risk of developing medullary thyroid cancer (MTC) and informs the timing of thyroidectomy. The efficacy of treatment,
Abdel-Aziz T, Brain C, Prete FP, Kurzawinski TR, the MEN2 in Children UK Collaborative Group, Morkane C   +5 more
core   +4 more sources

Cystic adrenal mass revealing a pheochromocytoma in the setting of multiple endocrine neoplasia: A case report

Radiology Case Reports
Pheochromocytoma, a neuroendocrine tumor, represents a rare medical condition characterized by the excessive secretion of catecholamines. These tumors often exhibit distinctive features on imaging studies, notably appearing hypervascular.
Hajar Zebbakh, Kaoutar Imrani, Taha Yassine Aaboudech, Zakia Bernoussi, Nabil MoatassimBillah, Ittimade Nassar   +5 more
doaj   +1 more source