Results 311 to 320 of about 236,698 (345)

Causal relationship between gut microbiota and metabolic syndrome: A bidirectional Mendelian randomization study. [PDF]

Medicine (Baltimore)
Ren Q, Cui C, Peng Y, Zhou Y, Zhang H, Chen L, Liu Z.   +6 more
europepmc   +1 more source

Multi‐Omic Associations of Epigenetic Age Acceleration Are Heterogeneously Shaped by Genetic and Environmental Influences

Aging Cell, EarlyView.
The connections between epigenetic age acceleration (EAA) and the multi‐ome, as well as the extent to which these connections are driven by genetic and environmental factors, remain underexplored. We identified blood proteins, metabolites, and exposures associated with EAA in young adults and, using twin study designs, show that these associations are ...
Gabin Drouard, Sannimari Suhonen, Aino Heikkinen, Zhiyang Wang, Jaakko Kaprio, Miina Ollikainen   +5 more
wiley   +1 more source

Exploring the causal effects of physical activity, diet, and nutrition on hypertension and hyperlipidemia: a multivariable Mendelian randomization analysis. [PDF]

BMC Cardiovasc Disord
Qian H, Liu Y, Choi H, Lee S.
europepmc   +1 more source

Risk of stroke accompanying alcohol consumption with or without single‐occasion drinking

Alcohol, Clinical and Experimental Research, EarlyView.
Previous studies on alcohol and stroke have highlighted several concerns. Notably, the conventional categorization based on average consumption, which categorizes both those who consume 20 g/day of alcohol daily and those who engage in risky single‐occasion drinking (RSOD) only on weekends into low drinkers, makes it difficult to account for ...
Midori Takada, Kazumasa Yamagishi, Isao Muraki, Yuji Shimizu, Mari Tanaka, Tomomi Kihara, Mitsumasa Umesawa, Hironori Imano, Tomoko Sankai, Takeo Okada, Akihiko Kitamura, Masahiko Kiyama, Hiroyasu Iso   +12 more
wiley   +1 more source

Depression reduces cognitive function partly through effects on BMI and hypertension: a large observational study and Mendelian randomization analysis. [PDF]

BMC Psychiatry
Gong H, Wang Z, Chen Y, Mi T, Wang Y.
europepmc   +1 more source

A historical perspective on Lionel Penrose: Scientist, geneticist and dedicated opponent of eugenics

Annals of Human Genetics, EarlyView.
Abstract The paper explores Lionel Penrose's scientific work. Penrose investigated the causes of mental disorders from clinical and genetic points of view. His investigations on phenylketonuria and Down syndrome helped to demonstrate the heterogenous character of mental disorders, whose causes can range from genetic with high penetrance, to largely ...
Maria Kiladi
wiley   +1 more source

Effects of agents acting on the renin-angiotensin system on the incidence of gastric cancer: A two-sample Mendelian randomization study. [PDF]

Medicine (Baltimore)
Lu H, Li F, Zhao D.
europepmc   +1 more source

Causal associations between inflammatory bowel disease and sepsis: a two-sample Mendelian randomization study. [PDF]

BMC Med Genomics
Tong R, Liang Z, Zhuo C, Bai X, Dao L, Yu L, Li L, Tong Z, Du Y, Xu L.   +9 more
europepmc   +1 more source

Mendelian randomization reveals probucol's preventive role in Behçet's disease via circulating metabolites. [PDF]

Sci Rep
Hongchen Z, Yijia Z, Yubo X, Jianguang Z, Mouyuan S, Jian L, Jin L.   +6 more
europepmc   +1 more source

Exploring the Impact of Neuroticism on Lung Cancer Risk: Insights From Mediated Mendelian Randomization. [PDF]

Brain Behav
Zhang J, Ma X, Liu Z, Wang H, Lu B, Wang Z.   +5 more
europepmc   +1 more source