Results 291 to 300 of about 1,141,533 (358)

Causal role of immunophenotypes in HIV-1 acquisition: insights from Mendelian randomization analysis. [PDF]

Sci Rep
Li N, He C.
europepmc   +1 more source

A Principled Framework for Mendelian Randomization in Oral Health Research

Journal of Periodontal Research, EarlyView.
This methodological article provides a clear and accessible overview of Mendelian randomization for oral health researchers, emphasizing the core assumptions needed for credible causal inference. Focusing on applications in oral health, particularly periodontitis, it highlights both the strengths and limitations of the study design in order to support ...
Nasir Z. Bashir, Mario Romandini, Moritz Kebschull, Konstantinos K. Tsilidis, Dominique S. Michaud, Stephen Burgess   +5 more
wiley   +1 more source

Causal relationship between plasma lipidome and rosacea: a Mendelian randomization analysis. [PDF]

Front Endocrinol (Lausanne)
Wang X, Zhu Z.
europepmc   +1 more source

Genetic Susceptibility to Periodontitis

Journal of Periodontal Research, EarlyView.
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley   +1 more source

Mendelian randomization analysis provides insights into the relationship between inflammatory bowel disease and skin cancer. [PDF]

Mol Clin Oncol
Rashid S, Usoltsev D, Gupta S, Artomov M, Tsao H.   +4 more
europepmc   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source

Mendelian randomization analysis of immune cell traits and their association with cervical cancer risk. [PDF]

Discov Oncol
Yu J, Zhang Y.
europepmc   +1 more source

Sleep Health and White Matter Integrity in the UK Biobank

Journal of Sleep Research, EarlyView.
ABSTRACT Many people experience impaired sleep health, yet knowledge about its neurobiological correlates is limited. As previous studies have found associations between white matter integrity and several sleep traits, white matter integrity could be causally implicated in poor sleep health.
Roxana Petri, Florian Holub, Julian E. Schiel, Bernd Feige, Martin K. Rutter, Sandra Tamm, Dieter Riemann, Simon D. Kyle, Kai Spiegelhalder   +8 more
wiley   +1 more source

Exploring the Relationship Between Caffeine Consumption, Caffeine Metabolism, and Sleep Behaviours: A Mendelian Randomisation Study

Journal of Sleep Research, EarlyView.
ABSTRACT Higher consumption of caffeinated beverages is associated with disturbed sleep patterns. Using genetic variants as proxies for caffeine consumption, caffeine metabolism, and sleep traits, we investigated whether this association reflects a direct effect of caffeine.
Nilabhra R. Das, Benjamin Woolf, Stephanie Page, Rebecca C. Richmond, Jasmine Khouja   +4 more
wiley   +1 more source