Results 21 to 30 of about 464 (130)

Toxicokinetic modelling of the synthetic cannabinoid 5F‐MDMB‐P7AICA and its main metabolite in pigs following pulmonary administration

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Since their emergence on the drug market, synthetic cannabinoids (SC) are still gaining increasing importance in forensic toxicology. The representatives of the so‐called new psychoactive substances have in common that they have not undergone preclinical safety studies. Hence, knowledge on toxicokinetic (TK) data is sparse.
Adrian A. Doerr   +10 more
wiley   +1 more source

Tolerability and Feasibility of Minimally Invasive Canine Skin Sampling: Excellent Tolerability Meets Transcriptomic Challenges

open access: yesVeterinary Dermatology, Volume 37, Issue 3, Page 375-385, June 2026.
ABSTRACT Background Advances in transcriptomics have driven the demand for minimally invasive, reproducible and high‐yield skin sampling methods, particularly for studying inflammatory skin diseases in companion animals. Hypothesis/Objectives We tested tolerability, feasibility and RNA quantity and quality of three minimally invasive skin sampling ...
Ina Herrmann   +2 more
wiley   +1 more source

Impact of a 12‐week high‐intensity interval training intervention on cardiac structure and function after COVID‐19 at 12‐month follow‐up

open access: yesExperimental Physiology, Volume 111, Issue 6, Page 2975-2986, 1 June 2026.
Abstract In patients previously hospitalised for COVID‐19, a 12‐week high‐intensity interval training (HIIT) intervention has previously been shown to increase left ventricular mass (LVM) immediately after the intervention. In the present study, we examined the effects of the same HIIT scheme on LVM, pulmonary diffusing capacity, symptom severity and ...
Iben Elmerdahl Rasmussen   +21 more
wiley   +1 more source

Characterizations of weaker forms of the Rothberger and Menger properties in hyperspaces

open access: yesFilomat, 2023
In this paper, we introduce the notions of almost ??(?)-network and weakly ??(?)-network to characterize the properties of almost Rothberger (Menger) and weakly Rothberger (Menger), respectively, in the hyperspaces CL(X),K(X), F(X) and CS(X), endowed with the hit-and-miss topology.
Ricardo Cruz-Castillo   +2 more
openaire   +1 more source

CMR‐derived left ventricular pressure‐volume loops enhance individualized assessment of disease severity and prognosis in pulmonary arterial hypertension in adults

open access: yesPhysiological Reports, Volume 14, Issue 11, June 2026.
Abstract In pulmonary arterial hypertension (PAH), increased pulmonary vascular resistance (PVR) causes right ventricular pressure overload and left ventricular (LV) underfilling. We investigated LV mechanics and their prognostic value in PAH using cardiovascular magnetic resonance (CMR)‐derived LV pressure‐volume (PV) loops.
Alessandro Castiglione   +5 more
wiley   +1 more source

The functional characterizations of the Rothberger and Menger properties

open access: yesTopology and its Applications, 2018
Let \(X\) be a Tychonoff space and \(C_p(X)\) be the space of all continuous real-valued functions defined on \(X\) with the topology of pointwise convergence. A space \(X\) is said to be Rothberger if for every sequence \(\{ \mathcal{U}_n : n \in\mathbb{N}\}\) of open covers of \(X\), there is a sequence \(\{ V_n : n \in\mathbb{N}\}\) such that \(V_n \
openaire   +2 more sources

Kinesin‐Induced Buckling Reveals the Limits of Microtubule Self‐Repair

open access: yesAdvanced Science, Volume 13, Issue 26, 8 May 2026.
This study shows that kinesin‐driven buckling induces extensive microtubule lattice damage that often exceeds intrinsic self‐repair and leads to filament failure. While curvature, motor motility, and force individually cause limited damage, their combination overwhelms repair.
Shweta Nandakumar   +9 more
wiley   +1 more source

Countable dense homogeneous filters and the Menger covering property [PDF]

open access: yesFundamenta Mathematicae, 2014
8 ...
Repovs, Dusan   +2 more
openaire   +3 more sources

Comparing Two Novel LiDAR‐Based Indices for Quantifying Forest Structural Complexity

open access: yesEcology and Evolution, Volume 16, Issue 5, May 2026.
This study compares two LiDAR‐derived forest structural complexity indices: the fractal‐based box dimension (Db$$ {D}_b $$) and the entropy‐based canopy entropy (CE$$ CE $$). Analysis of 170 plots revealed a strong linear correlation (r = 0.823) between Db$$ {D}_b $$ and CE$$ CE $$, but computation was much slower.
Tillman Reuter   +2 more
wiley   +1 more source

Endoscopically assessed mucus parameters in equine asthma: Relationship to clinical history and cytological findings data

open access: yesEquine Veterinary Journal, Volume 58, Issue 3, Page 767-778, May 2026.
Abstract Background Mucus parameters are hallmark diagnostic features of equine asthma (EA). Objectives To investigate the relationship between mucus quantity score and mucus viscosity score with signalment, history, clinical findings and cytological parameters. Study Design Retrospective cross‐sectional study.
Julia Drespling   +5 more
wiley   +1 more source

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