Efficacy of Multi-Modal Migraine Prophylaxis Therapy on Hyperacusis Patients. [PDF]
, 2020 ObjectivesTo evaluate the efficacy of a multi-modal migraine prophylaxis therapy for patients with hyperacusis.MethodsIn a prospective cohort, patients with hyperacusis were treated with a multi-modal step-wise migraine prophylactic regimen ...
Abouzari, Mehdi +7 more
core
Impact evaluation and association with EuroQol 5D health-related utility values in Meniere's disease [PDF]
, 2015 The study was aimed at evaluating the validity of impact measures among patients with Meniere's disease (MD) with outcome variables of EuroQol generic health-related quality of life (HRQoL) measures (i.e., EQ-5D) by using Visual Analogue Scale (VAS) and ...
Kentala, Erna +3 more
core +2 more sources
Intralabyrinthine Vestibular Schwannoma Responsive to Intratympanic Gentamicin Treatment [PDF]
, 2017 Intralabyrinthine schwannoma (ILS) is a rare benign tumor that affects the ends of cochlear and vestibular nerves. In a majority of the cases, it occurs with unilateral progressive sensorineural hearing loss.
Barbara, Maurizio +6 more
core +1 more source
Advanced Science, EarlyView.This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang +16 more
wiley +1 more source
Intratympanic gentamicin treatment for Ménière's disease: A randomized, double-blind, placebo-controlled trial on dose efficacy - results of a prematurely ended study [PDF]
, 2014 Background: Gentamicin is used as a therapeutic agent for Ménière's disease because of its vestibulotoxicity causing chemo-ablation of the vestibular sensory epithelia. Its use has increased in recent years. However, there is still no consensus about the
Bremer, H.G. (Hendrik G.) +9 more
core +4 more sources
Journal of Periodontology, EarlyView.Abstract Background Periodontitis is a widespread, chronic infection‐triggered inflammatory condition in which professional supportive periodontal care (SPC) and daily oral hygiene form the backbone to reduce the disease activity. Light‐based treatments have shown promising antibacterial effects, but their potential for routine home use has not been ...
Paula Tegelberg +9 more
wiley +1 more source
On the role of depletive tests. a review analysis [PDF]
, 2016 An overview of the diagnostic role of depletion tests for staging Meniere’s disease, especially in the first phase of the disease, is reported.
Barbara, M +4 more
core
Labyrinthine Abnormalities on MRI in Untreated Otosclerosis: Prevalence and Clinical Relevance
The Laryngoscope, EarlyView.In untreated otosclerosis with labyrinthine symptoms, delayed 3D FLAIR MRI rarely demonstrates endolymphatic hydrops but frequently reveals blood–labyrinth barrier (BLB) disruption. BLB enhancement is spatially associated with cochlear endosteal and round window involvement and increases with the severity of the hearing loss phenotype.
Héléna Pencroffi +7 more
wiley +1 more source
Cochlear Implantation in Autoimmune Inner‐Ear Disease: Outcome and Patient‐Reported Benefit
The Laryngoscope, EarlyView.This study demonstrates that patients with secondary autoimmune inner‐ear disease (AIED) achieve significant improvements in speech perception and quality of life following cochlear implantation. Although AIED patients may show slightly lower performance in noisy environments compared to controls, their subjective hearing benefit converges with matched
Merete Hartmann +4 more
wiley +1 more source
Evaluation of the usefulness of three-dimensional optical coherence tomography in a guinea pig model of endolymphatic hydrops induced by surgical obliteration of the endolymphatic duct [PDF]
, 2015 Optical coherence tomography (OCT) has advanced significantly over the past two decades and is currently used extensively to monitor the internal structures of organs, particularly in ophthalmology and dermatology.
Jang Woo Lee +7 more
core +2 more sources