Results 121 to 130 of about 112,287 (262)

Tumor immunogenicity shapes CNS immune niches and CD8⁺ T cell fate in glioblastoma. [PDF]

J Neuroinflammation
Asalla S, Ahumada OS, Krull JE, Wang Y, Patel DN, Gupta V, Wieland A, Giglio P, Ma Q, Tedeschi A, Segal BM, Acharya N.   +11 more
europepmc   +1 more source

Clobazam to preserve meaningful engagement in prolonged disorder of consciousness with concurrent seizure disorder

PM&R, EarlyView.
Tatiana Bernstein, Zachary Miklja, Tiffany Wood, Joshua Startup   +3 more
wiley   +1 more source

Zeb2 Controls Retinal Physiological and Pathological Angiogenesis by Regulating Astrocyte Proliferation and Differentiation

Cell Proliferation, EarlyView.
During development, the oxygen‐sensitive transcription factor Zeb2 restrains astrocyte proliferation and maturation to ensure balanced retinal angiogenesis. In disease, it promotes the neurotoxic A1 astrocyte phenotype and inflammation, thereby promoting reparative revascularization over pathological neovascularization.
Jing Liu, Yanan Guo, Kangjian Xiang, Shuyi Wang, Dongchang Xiao, Mengqing Xiang   +5 more
wiley   +1 more source

Evaluation of [¹⁸F]MK-6240 binding to tau protein in postmortem human brains of Down syndrome and Alzheimer's disease and assessment of off-target (non-tau) binding. [PDF]

Acta Neuropathol Commun
Karim F, Biju AP, Liang C, Santos CJ, Rajarethenam M, Mukherjee J.   +5 more
europepmc   +1 more source

Variation in rates of post-operative oncological treatment for patients with glioblastoma in England: a comprehensive multi-year National cohort study from the GlioCova project. [PDF]

J Neurooncol
Mauricaite R, Calvez KL, Robinson SD, Camp S, Brodbelt A, Booth TC, Williams M.   +6 more
europepmc   +1 more source

Astrocytic connexin43 phosphorylation contributes to seizure susceptibility after mild traumatic brain injury

The FEBS Journal, EarlyView.
Astrocytic gap junctions formed by connexin43 (Cx43) help maintain brain homeostasis. After mild traumatic brain injury (TBI), total cortical Cx43 increases and redistributes toward a soluble, non‐junctional pool with elevated hemichannel activity and increased phosphorylation at serine 368 (pCx43S368).
Carmen Muñoz‐Ballester, Owen Leitzel, Samantha Golf, Chelsea M. Phillips, Michael J. Zeitz, Rahul Pandit, Elizabeth Wash, Jenna V. Donohue, Elizabeth A. Istre, James W. Smyth, Samy Lamouille, Stefanie Robel   +11 more
wiley   +1 more source

The meninges as a neuroimmune interface: structure, barriers and roles in CNS disease. [PDF]

Fluids Barriers CNS
Joost S, Kaddatz H, Vankriekelsvenne E, Brandenburg LO.   +3 more
europepmc   +1 more source

Targeted liquid chromatography–tandem mass spectrometry profiling of arginine and histidine derivatives in chronic migraine: Discriminatory performance and changes after onabotulinumtoxinA therapy

Headache: The Journal of Head and Face Pain, EarlyView.
Plain Language Summary People with chronic migraine may have changes in amino‐acid metabolism, but it remains unclear which metabolic pathways are associated with the disease and early response to onabotulinumtoxinA treatment. We measured plasma amino‐acid levels in patients with chronic migraine and healthy controls and assessed changes after 1 month ...
Seyma Dumur, Kadidiatou Diarra, Joudy Sewidan, Julie Jalila Kalmoni, Demet Aygun, Dildar Konukoglu, Hafize Uzun   +6 more
wiley   +1 more source

Predictive factors of epidural blood patch success in intracranial hypotension syndrome

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective This study aimed to identify predictors of epidural blood patch (EBP) success in patients with intracranial hypotension syndrome. Background The epidural blood patch remains the gold standard treatment for intracranial hypotension syndrome, yet its effectiveness varies, and predictors of sustained success remain uncertain. Methods We
Anna Le Moal‐Baczynski, Alexandre Castelli, Vincent Doat‐Sarfati, Sylvain Redon, Anne Donnet, Nicolas Bruder, François Antonini, Jules Henri, Jean‐François Hak, Victor Lebreton, Jeanne Morel, Mehdi Assal, Lionel Velly, Pierre Simeone   +13 more
wiley   +1 more source

SynapTrack: An automated tool for synapse quantification

Journal of Microscopy, EarlyView.
Abstract Reliable synapse quantification remains challenging, particularly in high‐throughput fluorescence imaging workflows. Here we present SynapTrack, a fully automated FIJI/ImageJ‐based tool for quantifying synapses in cultured neurons and brain tissue sections with minimal user intervention.
Carlos Gallego‐García, Elena Martínez‐Blanco, F. Javier Díez‐Guerra   +2 more
wiley   +1 more source