Results 141 to 150 of about 122,319 (302)

The Crude Venom of the Whitetail Lancehead, Bothrops leucurus, and Two of Its Enzymatic Components Are Selectively Cytotoxic for Glioma Cells In Vitro

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Malignant glioma is the most common primary brain tumor, and glioblastoma multiforme (GBM) remains its most aggressive and incurable form. Snake venoms contain bioactive compounds with promising antitumoral properties against several cancer types.
M. O. H. V. Rosário   +7 more
wiley   +1 more source

Long‐Term Clinical Response After Low‐Dose and Short‐Duration Cemiplimab Therapy in a Patient With Xeroderma Pigmentosum in Nepal

open access: yesJEADV Clinical Practice, EarlyView.
Capsule Summary Xeroderma pigmentosum (XP) is associated with a high risk of multiple and aggressive cutaneous squamous cell carcinomas (CSCCs). The immune checkpoint inhibitor cemiplimab has been approved in advanced, unresectable, and/or metastatic CSCCs.
Sudip Parajuli   +5 more
wiley   +1 more source

Histología de las Fibras Nerviosas, Ganglios, Meninges y Nervios

open access: yes
Campedindio de conocimientos de Histología de las Fibras Nerviosas, Ganglios, Meninges y NerviosBiología Celular, Genética, Histología y ...
Fernández Lázaro, Diego
core  

Idiopathic Intracranial Hypertension Associated With Transverse Sinus Giant Arachnoid Granulation Successfully Treated by Endovascular Stenting

open access: yesNeurology and Clinical Neuroscience, EarlyView.
ABSTRACT The incidence of Idiopathic intracranial hypertension (IIH), defined as increased intracranial pressure of unknown origin, has been reported to be very low in Japan. A 42‐year‐old Japanese woman was admitted to our hospital with headache, blurred vision, and tinnitus.
Hiroka Sakaguchi   +10 more
wiley   +1 more source

Chronic high‐altitude exposure and intracerebral hemorrhage: A novel perspective from the vascular‐immune‐neuronal network

open access: yesNeuroprotection, EarlyView.
Long‐term chronic high‐altitude hypobaric hypoxia increases susceptibility to ICH, particularly among migrant populations lacking EPAS1/SENP1 adaptive genetic variants relative to high‐altitude indigenous residents. Persistent hypoxia initiates blood–brain barrier (BBB) breakdown, aberrant glial and immune activation, and progressive neuronal injury ...
Rongsu Huang   +6 more
wiley   +1 more source

Microglia Ablation and Downstream Effects in the Cerebrospinal Fluid Proteome

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Disease‐related activation of glial cells leads to changes in the cerebrospinal fluid (CSF) proteome. However, assigning such protein changes to their cellular origins is often difficult. Here, we used microglia (and macrophage) depletion in mice to identify CSF proteins of microglial origin.
Sinja Buchner   +8 more
wiley   +1 more source

Corrigendum: Living on the Edge of the CNS: Meninges Cell Diversity in Health and Disease

open access: yesFrontiers in Cellular Neuroscience, 2021
Julia Derk   +8 more
doaj   +1 more source

Apigenin Protects Hypertensive Intracerebral Hemorrhage by Regulating Trx1 Through Binding to PRDX2

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Intracerebral hemorrhage (ICH) remains the most severe stroke subtype with high mortality and disability rates. Although apigenin has shown cerebroprotective potential in preclinical studies, its mechanism of action, particularly in hypertensive ICH, remains poorly understood.
Hao‐chen Xu   +6 more
wiley   +1 more source

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