Slit2/Robo Signaling Restores Diabetic Erectile Function via Neurovascular Remodeling
ABSTRACT Background Diabetes mellitus‐induced erectile dysfunction (DMED) is a common and debilitating vascular‐neurogenic complication of diabetes. The poor responsiveness of DMED patients to phosphodiesterase type‐5 inhibitors underscores the need for therapies capable of restoring both endothelial integrity and cavernous nerve function.
Sen Fu +7 more
wiley +1 more source
Epidermoid cyst as differential diagnosis for spherical keratoma: What do we know?
Summary This article briefly presents the case of a space‐occupying coronary band mass that raised the question of how one can differentiate between two uncommonly seen but now commonly paired differential diagnoses and prompted a review of the relevant literature.
R. Goodman‐Davis +2 more
wiley +1 more source
Cooling down for going up: Could selective ‘brain chilling’ mitigate high‐altitude illness?
Experimental Physiology, EarlyView.
Adnan Haq, Damian M. Bailey
wiley +1 more source
Perineurioma‐like EMA‐positive calvarial neoplasms: clinicopathological study of eight cases
Perineurioma‐like, EMA‐positive calvarial neoplasms (PLECN) are a rare group of intraosseous spindle cell tumours that demonstrate overlapping morphologic features of perineurioma and fibroblastic meningioma. These lesions tend to behave indolently but show a propensity for progressive growth.
Raheel Rizwan +9 more
wiley +1 more source
Off-target binding of <sup>18</sup>F-MK-6240 tau PET imaging demonstrated by high spatial resolution dedicated brain PET scanner. [PDF]
Ishii K +8 more
europepmc +1 more source
Targeting progressive multiple sclerosis: Toward mechanism‐informed precision medicine
Abstract Multiple sclerosis has undergone a therapeutic revolution over the past three decades. Randomized clinical trials and real‐world data demonstrate that modern disease‐modifying therapies substantially reduce relapse rates and acute inflammatory activity detected by magnetic resonance imaging (MRI).
Fredrik Piehl +3 more
wiley +1 more source
Expression of Connexins 37/40 and Pannexin 1 in Early Human and <i>Yotari</i> (<i>Dab1<sup>-/-</sup></i>) Meninges Development. [PDF]
Puljiz M +5 more
europepmc +1 more source
Temporins, among antimicrobial peptides, are short frog‐derived molecules with potent antibacterial activity. This review highlights chemical optimization strategies applied to temporins A–L, showing how sequence tuning modulates structure, stability, and selectivity, enabling improved activity against resistant pathogens.
Ida Boccino +2 more
wiley +1 more source
Clinical heterogeneity and immunotherapy outcomes in anti-GAD65 antibody-associated autoimmune encephalitis: a retrospective study. [PDF]
Qiu Y +8 more
europepmc +1 more source

