Results 181 to 190 of about 112,287 (262)

Harnessing Repurposed Drugs to Enhance Temozolomide Efficacy in Glioblastoma

Cancer Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Glioblastoma (GB) is the most aggressive primary malignant brain tumor in adults and remains associated with poor survival despite surgical resection followed by radiotherapy and temozolomide (TMZ) chemotherapy. Intrinsic and acquired resistance to TMZ, including MGMT‐dependent DNA repair and activation of pro‐survival pathways ...
Ali Nakhaei, Atefeh Taghavi, Amir R. Afshari, Farzaneh Davoudi, Elaheh Gheybi, Mohammad Jalili‐Nik   +5 more
wiley   +1 more source

Glymphatic Dysfunction in Children With Type 2 and 3 Spinal Muscular Atrophy

CNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
This study reveals glymphatic dysfunction in children with spinal muscular atrophy (SMA), characterized by increased cerebrospinal fluid volume and reduced ALPS index. These alterations correlate with clinical severity, identifying glymphatic dysfunction as a previously unrecognized feature of SMA pathophysiology.
Shasha Lan, Pei Xiang, Cui Yan, Huirong Nie, Huan Wang, Boyan Xu, Zhiyun Yang, Wen Tang, Yijuan Li, Yujian Liang, Yingqian Chen   +10 more
wiley   +1 more source

Single-cell omics and flow cytometry identify distinct immune states of dural and brain-infiltrating IL-17-producing γδ T cells after experimental stroke. [PDF]

J Neuroinflammation
Zha M, Jander A, Cai H, Piepke M, Degenhardt K, Winter L, Magnus T, Gelderblom M.   +7 more
europepmc   +1 more source

Stromal Cell-Mast Cell Communication Orchestrates Anti-Viral Immunity in the Meninges. [PDF]

Adv Sci (Weinh)
Li Q, Chen W, Sun M, Ni X, Ran Q, Hu X, Cao F, Zeng W.   +7 more
europepmc   +1 more source

Yin Yang 1 Specifically Supports the Development of Olig2 Positive Cerebellar Astrocytes

Glia, Volume 74, Issue 8, August 2026.
Cerebellar Olig2 positive astrocytes are most abundant in the cerebellar nuclei. Cerebellar astrocytes expressing Olig2 have unique gene expression profiles. Yin Yang 1 specifically supports the development of astrocytes expressing Olig2. Deletion of YY1 during development increases numbers of astrocytes expressing Olig2 but hinders their ...
Masoumeh Zarei‐Kheirabadi, Katarzyna M. Tyc, Lauren Dain, Maryam Ashrafi Kheirabadi, Jennifer Hanco, Karli Mockenhaupt, Soha Munir, Adam McQuiston, Sandeep K. Singh, Tomasz Kordula   +9 more
wiley   +1 more source

From origins to nomenclature: illuminating the landscape of CNS fibroblasts and fibroblast-like cells. [PDF]

Acta Neuropathol Commun
Lin J, Liao K, Lewandowski SA.
europepmc   +1 more source

Use of Free Flaps in the Reconstruction of the Ventral Skull Base: A Systematic Literature Review

Head &Neck, Volume 48, Issue 8, Page 2261-2270, August 2026.
ABSTRACT Background Reconstruction of the ventral skull base represents a challenge in head and neck surgery. When local or regional flaps are insufficient, microvascular free flaps offer a reliable reconstructive option. Methods A systematic literature review was conducted following PRISMA guidelines to identify studies on ventral skull base ...
Francesco Mazzola, Francesco Benvegnù, Milena Fior, Martina Conti, Stefano Taboni, Enzo Emanuelli, Philippe Herman, Piero Nicolai, Elisabetta Zanoletti, Raul Pellini, Marco Ferrari   +10 more
wiley   +1 more source

Living rent free in your head: resident memory T cells. [PDF]

Immunohorizons
Degefu HN, Kleist SA, Rosato PC.
europepmc   +1 more source

Prognostic Value of Cranial Nerve Invasion in T4‐Stage Nasopharyngeal Carcinoma: A Retrospective Cohort Study With a Median Follow‐Up of 136 Months

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background The objective of this study was to evaluate the prognostic value of cranial nerve invasion (CNI) in T4‐stage nasopharyngeal carcinoma (NPC) patients with nonmetastatic. Methods We retrospectively analyzed 299 T4‐stage NPC patients with nonmetastatic disease in the Cancer Hospital of Shantou University Medical College.
Cuidai Zhang, Hui Liu, Xuejia Liu, Yihao Ye, Zeman Cai, Zewei Chen, Qizhi Zheng   +6 more
wiley   +1 more source

Leptomeninges: Anatomy, Mechanisms of Disease and Neuroimaging. [PDF]

Neurol Int
Zedde M, Pascarella R.
europepmc   +1 more source