Results 151 to 160 of about 115,799 (305)

Data‐driven thresholds for standardized classification of severe Alzheimer's disease neuropathology using digital neuropathology

Brain Pathology, EarlyView.
We generated digital pathologic algorithms (AI‐based modules that can be freely shared) to: optimize the sampling (ROI) for diagnosis of ADNC‐related tau pathology; compare/transition between Aperio and HALO platforms; and rationalize severe Braak NFT staging, so that all Braak‐VI cases had dementia, and all Braak‐V cases had MCI or dementia.
Ryan K. Shahidehpour, Allison M. Neltner, Mitchell A. Klusty, Cole Corbett, Angelique D. Gonzalez, David A. Gutman, David W. Fardo, Adam D. Bachstetter, Cody Bumgardner, Margaret E. Flanagan, Peter T. Nelson   +10 more
wiley   +1 more source

Nucleotide homeostasis and purinergic nociceptive signaling in rat meninges in migraine-like conditions

, 2020
© 2016, Springer Science+Business Media Dordrecht.Extracellular ATP is suspected to contribute to migraine pain but regulatory mechanisms controlling pro-nociceptive purinergic mechanisms in the meninges remain unknown.
Yegutkin G., Koroleva K., Kilinc E., Ishchenko Y., Giniatullin R., Abushik P., Fayuk D., Giniatullina R., Guerrero-Toro C.   +8 more
core  

Zeb2 Controls Retinal Physiological and Pathological Angiogenesis by Regulating Astrocyte Proliferation and Differentiation

Cell Proliferation, EarlyView.
During development, the oxygen‐sensitive transcription factor Zeb2 restrains astrocyte proliferation and maturation to ensure balanced retinal angiogenesis. In disease, it promotes the neurotoxic A1 astrocyte phenotype and inflammation, thereby promoting reparative revascularization over pathological neovascularization.
Jing Liu, Yanan Guo, Kangjian Xiang, Shuyi Wang, Dongchang Xiao, Mengqing Xiang   +5 more
wiley   +1 more source

Tuberculous Meningitis [PDF]

BMJ, 1952
openaire   +4 more sources

Corrigendum: Living on the Edge of the CNS: Meninges Cell Diversity in Health and Disease

Frontiers in Cellular Neuroscience, 2021
Julia Derk, Hannah E. Jones, Hannah E. Jones, Christina Como, Christina Como, Bradley Pawlikowski, Julie A. Siegenthaler, Julie A. Siegenthaler, Julie A. Siegenthaler   +8 more
doaj   +1 more source

Melanoma maligno primario de las meninges

, 2019
El melanoma maligno primario de las meninges es una neoplasia infrecuente de difícil diagnostico antes de la muerte debido a que no presenta un cuadro clínico o radiológico característico.
Garcia Ayala, Ernesto, Casas, Paula Andrea, Montero Pardo, Aldemar, Zamora Cabrera, Kleber   +3 more
core  

Astrocytic connexin43 phosphorylation contributes to seizure susceptibility after mild traumatic brain injury

The FEBS Journal, EarlyView.
Astrocytic gap junctions formed by connexin43 (Cx43) help maintain brain homeostasis. After mild traumatic brain injury (TBI), total cortical Cx43 increases and redistributes toward a soluble, non‐junctional pool with elevated hemichannel activity and increased phosphorylation at serine 368 (pCx43S368).
Carmen Muñoz‐Ballester, Owen Leitzel, Samantha Golf, Chelsea M. Phillips, Michael J. Zeitz, Rahul Pandit, Elizabeth Wash, Jenna V. Donohue, Elizabeth A. Istre, James W. Smyth, Samy Lamouille, Stefanie Robel   +11 more
wiley   +1 more source

Imaging and physiology across the high–low cerebrospinal fluid pressure spectrum: Navigating diagnostic uncertainty in headache practice

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective This study was conducted to provide a clinically oriented, mechanism‐based framework for interpreting neuroimaging across disorders of cerebrospinal fluid (CSF) pressure, with particular emphasis on patients who fall between classic diagnostic categories of spontaneous intracranial hypotension (SIH) and idiopathic intracranial ...
Andrew L. Callen, Kyle Jenkins
wiley   +1 more source

Current evidence on the cell of origin of meningiomas disputes the arachnoid cap cell dogma. [PDF]

Acta Neurochir (Wien)
Pamir MN, Erşen-Danyeli A, Özduman K.
europepmc   +1 more source

Lifestyle triggers of migraine: Sleep restriction and caffeine lower the threshold for migraine‐like responses in rats in a sex‐specific manner

Headache: The Journal of Head and Face Pain, EarlyView.
Sleep restriction (SR) and caffeine intake act as environmental modulators of migraine susceptibility. Their effects are sex‐dependent: Females show heightened sensitivity under both SR and caffeine conditions. Males require the combination of SR and caffeine to exhibit susceptibility.
Gabriel Camargo de Oliveira, Darciane Favero Baggio, Vanessa Bordenowsky Pereira Lejeune, Laura Storithont Quinelato, Fernanda Mariano Ribeiro da Luz, Aleksander Roberto Zampronio, Luana Fischer, Juliana Geremias Chichorro   +7 more
wiley   +1 more source