The Journal of Physiology, EarlyView.Abstract figure legend Paracetamol (acetaminophen) is commonly taken during pregnancy for pain and fever. To gain a more comprehensive understanding of paracetamol's effects during pregnancy, several elements need to be examined including the transfer of paracetamol across the placenta and into the developing brain, the short‐ and long‐term effects of ...
Yifan Huang, Liam Koehn
wiley +1 more source
Beyond the ischemic brain: Expanding single-cell transcriptomics in stroke research to extracentral nervous system systems, biological contexts, and poststroke complications. [PDF]
Brain CircMu C, Geng X, Schehr A, Ding Y.
europepmc +1 more source
High‐altitude headache: Insights into pathophysiology and potential treatment implications
The Journal of Physiology, EarlyView.Abstract figure legend High‐altitude headache occurs during prolonged exposure to low oxygen, such as during ascent to high altitude. Several risk factors increase its likelihood, with the degree of hypoxia, often driven by rapid ascent to greater altitudes, being the most prominent factor.
Marika Falla +3 more
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Cerebrospinal Fluid as a Window into Neuroimmune Responses During Brain Infection. [PDF]
CellsSingh G, Rohlwink UK.
europepmc +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend This study assessed the impact of plasma‐derived small extracellular vesicles (sEVs) from healthy pregnant women and those diagnosed with late‐onset preeclampsia (PE) on the blood–brain barrier (BBB) integrity and glial cell response. PE patients had higher sEV concentrations than healthy controls.
Julián Henao‐Restrepo +7 more
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The Aging Meninges: Anatomical and Immunological Remodeling as Emerging Diagnostic Biomarkers of Cerebral Senescence-A Narrative Review. [PDF]
Diagnostics (Basel)Chirica SI +4 more
europepmc +1 more source
Glia, Volume 75, Issue 1, January 2027.sox17 is a maternal effect gene impacting microglia and microglia precursor abundance. sox17 mRNA injection timed to maternal contribution rescues abundance. A CRISPR screen reveals f11r.1, gas6, and mpp1 also regulate microglia abundance. ABSTRACT Embryonic development is shaped by maternal and zygotic factors but how the interplay between these ...
Camden A. Spring +4 more
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Central nervous system antituberculosis drug exposures in a rabbit model of tuberculous meningitis. [PDF]
Antimicrob Agents ChemotherCalderin JM +12 more
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Microglial Labeling in Mouse Spinal Cord Injury: A Review of Timing, Efficacy, and Specificity
Glia, Volume 74, Issue 12, December 2026.The transcriptional profile of microglia is significantly altered after spinal cord injury (SCI). When choosing a marker to label microglia after SCI, it is important to consider its specificity for microglia and its stability of expression. ABSTRACT Traumatic spinal cord injury (SCI) is a complex and disabling condition with no curative therapy ...
Ruth Colbert +2 more
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Mechanical Characterization of Cervical Spinal Cord Tissue Under Varied Environmental Conditions
Proceedings in Applied Mathematics and Mechanics, Volume 26, Issue 4, December 2026.ABSTRACT Identifying material parameters for cervical spinal cord tissue requires an understanding of how testing protocols affect the measured response. We use ovine cervical spinal cord white matter to examine the effects of hydration, temperature, adhesive fixation and repeated loading.
Hanwen Zhang, Bernd Markert
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