Results 61 to 70 of about 115,799 (305)
, 2017 Non-meningothelial tumours of the meninges constitute a rare but diverse group of pathologies and consist of mesenchymal, melanocytic, and metastatic lesions.
Sith Sathornsumetee +3 more
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Advanced Science, EarlyView.Dysregulated TCA cycle contributes to Alzheimer's disease (AD) pathogenesis. Here, we show that microglial isocitrate dehydrogenase 1 (IDH1) is a critical driver. Elevated IDH1 disrupts citrate metabolism and mitochondrial function, exacerbating AD pathology.
Qianqian Li +13 more
wiley +1 more source
Advanced Science, EarlyView.This study reveals that Alzheimer's disease–linked APP expression in bone‐forming cells drives skull bone marrow remodeling and alters its vascular connections to the brain. These changes disrupt immune cell trafficking, cerebral blood flow, and cognition. Targeting bone marrow macrophages restores brain function, highlighting a previously unrecognized
Lei Xiong +6 more
wiley +1 more source
Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics
Advanced Intelligent Discovery, EarlyView.Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong +5 more
wiley +1 more source
Meningitis, Meninges, Meninx [PDF]
European Neurology, 2008 But meningitis has its verbal roots in the older anatomical term meninx , plural meninges . The OED tells us that meninx came from the post-classical Latin (attested about 1553 but probably earlier) whose plural form meninges is of 6th century origin.
openaire +1 more source
The Anatomical Record, EarlyView.Abstract In birds, the neural canal houses a variety of anatomical structures including the spinal cord, meninges, spinal vasculature, and respiratory diverticula. Among these, paramedullary diverticula and the extradural dorsal spinal vein may leave behind osteological correlates in the form of pneumatic foramina and fossae, and a bilobed geometry of ...
Jessie Atterholt +5 more
wiley +1 more source
Meninges: from protective membrane to stem cell niche [PDF]
, 2012 Meninges are a three tissue membrane primarily known as coverings of the brain. More in depth studies on meningeal function and ultrastructure have recently changed the view of meninges as a merely protective membrane.
G. Fumagalli +9 more
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Cerebral Vasculature, Cerebrospinal Fluid, & Meninges
, 2017 This chapter focuses on learning about the cerebral vasculature, cerebrospinal fluid, and the meninges. Instructions are given for drawing the circle of Willis, brainstem, cerebellar arteries, intracranial hemorrhage, brain herniation, cerebral ...
Adam J Fisch
core +1 more source
Appearance of the canine meninges in subtraction magnetic resonance images [PDF]
, 2014 The canine meninges are not visible as discrete structures in noncontrast magnetic resonance (MR) images, and are incompletely visualized in T1‐weighted, postgadolinium images, reportedly appearing as short, thin curvilinear segments with minimal ...
Keenihan, E K +3 more
core +1 more source
The Anatomical Record, EarlyView.Abstract The vertebrate skull is composed of bones derived from neural crest cells and mesoderm. The evolutionary capacity of the skull has been linked, in part, to the emergence of neural crest cells; however, this increased capacity for evolutionary change requires that variation within neural crest‐ and mesoderm‐derived bones remains partly ...
Alyssa C. Moore +5 more
wiley +1 more source