Results 71 to 80 of about 122,319 (302)

Neuron‐Derived Vesicular circMagi1 Restrains Vascular Repair After Ischemic Stroke by Promoting TRIM65‐Mediated ANXA2 Degradation

open access: yesAdvanced Science, EarlyView.
After ischemic stroke, injured neurons transfer circMagi1 to endothelial cells through extracellular vesicles. Within endothelial cells, circMagi1 binds ANXA2 and enhances its engagement with TRIM65, promoting ANXA2 ubiquitination and proteasomal degradation to constrain angiogenic repair.
Youkun Bi   +16 more
wiley   +1 more source

Investigating immune-stroma signaling landscape in the developing meninges

open access: yes, 2022
UndergraduateRecent research has revealed that populations of immune cells outside of the brain parenchyma influence the brain itself. These immune cells are located in border tissues such as the meninges.
Lanser, Toby B   +5 more
core  

Lactylation‐Driven PROS1‐TYRO3‐CARF Signaling Promotes Therapy‐Induced Senescence Escape and Radioresistance in Meningioma

open access: yesAdvanced Science, EarlyView.
A glycolysis‐driven epigenetic switch promotes therapy resistance in meningioma. Increased lactate production enhances histone H3K27 lactylation, which activates PROS1 secretion. Secreted PROS1 engages TYRO3 signaling to degrade the senescence regulator CARF, allowing cancer cells to escape growth arrest.
Zhuohang Wang   +12 more
wiley   +1 more source

Meninges

open access: yes, 2009
Siete imágenes de meninges.Seven pictures of ...
Iglesias Rozas, José Rafael, 1942-
core  

Phospholipase B in the Brains and Meninges of Nonsensitized and Sensitized Rats After Challenge with Angiostrongylus cantonensis [PDF]

open access: yes, 1980
After a primary infection with 100 Angiostrongylus cantonensis larvae, infected rats showed elevated phospholipase B activity in meningeal and brain homogenates beginning with the first week and continuing through the first month of infection.
Ottolenghi, Athos   +2 more
core   +1 more source

Temporal Trajectories of the Tau Aggregate Interactome Reveal Stage‐Specific Vulnerabilities in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
Tau populations with different aggregation states associate with distinct sets of proteins in the Alzheimer's disease brain. Proteomic discovery combined with single‐molecule analysis in neurons reveals dynamic associations involving proteostasis, metabolism and RNA biology.
Dorothea Böken   +8 more
wiley   +1 more source

Astrocitoma en meninges

open access: yes, 2009
Imagen de un astrocitoma en las meninges de un paciente de 7 años.Picture of an astrocytoma in the meninges of a 7-year-old male ...
Iglesias Rozas, José Rafael, 1942-
core  

Neonatal Sevoflurane Exposure Induces Long‐Term Cognitive Impairment via Epigenetically Mediated MMP9 Activation and Perineuronal Net Disruption in the Hippocampal CA2

open access: yesAdvanced Science, EarlyView.
Hippocampal CA2 perineuronal nets ensheathing excitatory pyramidal neurons are selectively vulnerable to repeated neonatal sevoflurane exposure. Epigenetic upregulation of MMP9 via reduced H3K27me3 disrupts PNN integrity, impairs BDNF–TrkB signaling, and causes synaptic protein loss and dendritic spine deficits, leading to persistent social and spatial
Lirong Liang   +11 more
wiley   +1 more source

Oligoastrocitoma infiltrante en meninges

open access: yes, 2009
Tres imágenes de un oligoastrocitoma infiltrante en las meninges en una paciente de 10 años.Three pictures of an oligoastrocytoma infiltrated in the meninges in a 10-year-old female ...
Iglesias Rozas, José Rafael, 1942-
core  

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