Results 101 to 110 of about 45,550 (255)

The Functional Role and Molecular Characterization of the Therapeutic Target CLDN6 in Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Background The tight junction protein CLDN6 has been identified as a cancer‐associated cell surface marker that is rarely expressed in healthy tissues. In testicular germ cell tumors (GCT), CLDN6 is particularly detectable in seminomas, embryonal carcinomas, and choriocarcinomas.
Jule Zwick, Margaretha A. Skowron, Gereon Poschmann, Patrick Petzsch, Ann Kathrin Bergmann, Kai Stühler, Jochen Hecht, Daniel Nettersheim   +7 more
wiley   +1 more source

CT in small animal brain diseases [PDF]

, 2013
C
Gielen, Ingrid, Kromhout, Kaatje, van Bree, Henri   +2 more
core   +1 more source

Recurrent somatic mutations in POLR2A define a distinct subset of meningiomas [PDF]

, 2016
RNA polymerase II mediates the transcription of all protein-coding genes in eukaryotic cells, a process that is fundamental to life. Genomic mutations altering this enzyme have not previously been linked to any pathology in humans, which is a testament ...
A Gulhan Ercan-Sencicek, A Sadanandam, AB Olshen, Abraham S Weintraub, Akdes Serin Harmancı, Alexander O Vortmeyer, AS Bhagwat, B Langmead, BJ O'Roak, Boris Krischek, Brian J Abraham, C Isella, C Trapnell, CS Ross-Innes, CY Lin, D Hnisz, D Kim, Daniel Durán, DE Reuss, Denes Hnisz, E Chipumuro, E Zeynep Erson-Omay, F De Sousa E Melo, G Lunter, Geneive Carrión-Grant, H Li, H Li, H Li, H Thorvaldsdóttir, Hanwen Bai, J Cotney, J Lovén, J Lovén, J Schwartzentruber, Jacob F Baranoski, Jennifer Moliterno Günel, JF Sathirapongsasuti, Johanna E Goldmann, Johannes Schramm, Joseph M Piepmeier, JT Leek, K Bilgüvar, K Chen, K Kämpjärvi, Katsuhito Yasuno, Kaya Bilgüvar, Ketu Mishra-Gorur, L Santi, LS Kirschner, M Aavikko, M Abedalthagafi, M Gymnopoulos, M Wintzerith, MA Davies, MA DePristo, Mark W Youngblood, Matthias Simon, MD Wilkerson, Murat Günel, Octavian Henegariu, PK Brastianos, Q Cui, QT Ostrom, R Gaujoux, R Tibshirani, RG Verhaak, Richard A Young, Roland Goldbrunner, T Inoue, T Kotani, TL Bailey, Tong Ihn Lee, U Schmitz, VE Clark, VG Tusher, Victoria E Clark, W Huang, WA Whyte, XH Wu, Y Choe, Y Rifat, Y Zhang   +81 more
core   +1 more source

Using continuous visual stimulus tracking for detecting visual function loss due to acquired brain injury

Acta Ophthalmologica, EarlyView.
Abstract Purpose Acquired brain injury (ABI) may cause homonymous visual field (VF) defects. Standard automated perimetry (SAP) is the gold standard for VF assessment, but it can be challenging in ABI. Continuous visual stimulus tracking (SONDA; Standardised Oculomotor and Neurological Disorders Assessment) simplifies the perimetric task to following a
A. C. L. Vrijling, M. J. de Boer, R. J. Renken, J. B. C. Marsman, J. Heutink, F. W. Cornelissen, N. M. Jansonius   +6 more
wiley   +1 more source

A robust adaptive wavelet-based method for classification of meningioma histology images [PDF]

, 2009
Intra-class variability in the texture of samples is an important problem in the domain of histological image classification. This issue is inherent to the field due to the high complexity of histology image data.
Hans, Volkmar, Nattkemper, Tim W., Qureshi, Hammad A., Rajpoot, Nasir M. (Nasir Mahmood)   +3 more
core  

Metastatic meningioma: positron emission tomography CT imaging findings [PDF]

, 2005
The imaging findings of a case of metastasing meningioma are described. The case illustrates a number of rare and interesting features. The patient presented with haemoptysis 22 years after the initial resection of an intracranial meningioma.
Brennan, Cressida R., Dineen, J., Hinchion, John, Keohane, Catherine, Maher, Michael M., O'Connor, Owen J., O'Regan, Kevin N., Sweeney, Brian J.   +7 more
core   +1 more source

Ultrasound, PET/CT or temporal artery biopsy for giant cell arteritis? A prospective diagnostic accuracy study (the GAME‐study)

Acta Ophthalmologica, EarlyView.
Abstract Purpose To investigate the diagnostic performance of ultrasound, 2‐deoxy‐2‐[18F]fluoro‐D‐glucose positron emission tomography/computed tomography (2‐[18F]FDG PET/CT) and temporal artery biopsy (TAB) in giant cell arteritis (GCA). Methods This was a prospective single‐centre diagnostic accuracy study (ClinicalTrials.gov NCT05248906).
Michael S. Hansen, Lene Terslev, Uffe M. Døhn, Viktoria Fana, Jane M. Brittain, Anne K. Wiencke, Steffen Heegaard, Mads R. Jensen, Oliver N. Klefter, Yousif Subhi, Steffen Hamann   +10 more
wiley   +1 more source

Comparative analysis of spatial and transform domain methods for meningioma subtype classification [PDF]

, 2010
Pattern recognition in histopathological image analysis requires new techniques and methods. Various techniques have been presented and some state of the art techniques have been applied to complex textural data in histological images.
Qureshi, Hammad A., Rajpoot, Nasir M. (Nasir Mahmood)   +1 more
core  

Optic nerve sheath meningioma exhibits neural niche‐associated transcriptomic features and rare copy number variation‐linked evolution

Brain Pathology, EarlyView.
Optic nerve sheath meningiomas are typically NF2‐intact with few copy number alterations and are generally clinically indolent. Rare aggressive recurrences are associated with progressive accumulation of copy number variations, including CDKN2A/B homozygous deletion, 1q gain, and 14q loss.
Daisuke Sato, Satoru Miyawaki, Yu Sakai, Kenta Ohara, Yu Teranishi, Yudai Hirano, Motoyuki Umekawa, Takahiro Tsuchiya, Shotaro Ogawa, So Hirata, Hiroki Hongo, Hideaki Ono, Daisuke Komura, Tetsuo Ushiku, Shumpei Ishikawa, Nobuhito Saito   +15 more
wiley   +1 more source

Glioma Diagnosis Aid through CNNs and Fuzzy-C Means for MRI [PDF]

, 2019
Glioma is a type of brain tumor that causes mortality in many cases. Early diagnosis is an important factor. Typically, it is detected through MRI and then either a treatment is applied, or it is removed through surgery.
Amaya Rodríguez, Isabel, Cascado Caballero, Daniel, Civit Balcells, Antón, Civit Masot, Javier, Domínguez Morales, Juan Pedro, Durán López, Lourdes, Linares Barranco, Alejandro, Luna Perejón, Francisco, Vicente Díaz, Saturnino   +8 more
core