Results 131 to 140 of about 45,550 (255)
BackgroundHigh expression of Ki-67 in meningioma is significantly associated with higher histological grade and worse prognosis. The non-invasive and dynamic assessment of Ki-67 expression levels in meningiomas is of significant clinical importance and ...
Ming Luo +12 more
doaj +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Visual outcomes in patients with meningiomas compressing optic nerve
BackgroundMeningiomas compressing the optic nerve can lead to progressive visual loss due to the nerve’s complex intraorbital, intracanalicular, and intracranial anatomy.
David Krahulik +5 more
doaj +1 more source
Automated identification of radiotherapy treatment sites from unstructured physician notes
Abstract Purpose Ambiguous or incomplete documentation is a recurrent bottleneck in radiation oncology workflows, leading to inefficiencies in communication and potential treatment delays. Large language models (LLMs) pose a solution to addressing these ambiguities without added burden to clinical staff.
Klea Hoxha +5 more
wiley +1 more source
Genomic landscape of high-grade meningiomas [PDF]
Artyomov, Maksym +3 more
core +2 more sources
His‐MMDM: Multi‐Domain and Multi‐Omics Translation of Histopathological Images with Diffusion Models
His‐MMDM is a diffusion model‐based framework for scalable multi‐domain and multi‐omics translation of histopathological images, enabling tasks from virtual staining, cross‐tumor knowledge transfer, and omics‐guided image editing. ABSTRACT Generative AI (GenAI) has advanced computational pathology through various image translation models.
Zhongxiao Li +13 more
wiley +1 more source
Abstract Objective To investigate a recently developed MRI technique for mapping the Mean Diffusivity of Tissue (MDT), which improves diffusion MRI imaging of the cerebral cortex by reducing partial volume effects from cerebrospinal fluid (CSF). As cortical lesions are common in patients with focal epilepsy, we explored the clinical value of MDT ...
Irena Grubor +5 more
wiley +1 more source
Real‐World Weight Loss Is Associated With a Reduction in Cancer Risk
ABSTRACT Objective Obesity is a major risk factor for multiple cancers, yet the impact of nonsurgical weight loss on cancer risk remains uncertain. Our objective was to evaluate whether real‐world nonsurgical weight loss is associated with a reduced risk of developing cancer.
Kenda Alkwatli +7 more
wiley +1 more source
We report a genetically confirmed case of adult‐onset congenital central hypoventilation syndrome (CCHS) in a 69‐year‐old man whose condition became clinically manifest following transsphenoidal surgery for a pituitary microadenoma, complicated by high‐grade atrioventricular block and recurrent postoperative type 2 respiratory failure.
Sushil Agwan +2 more
wiley +1 more source
Early Initiation of Adjuvant Therapy Following Pediatric Endoscopic Endonasal Surgery for Tumors
ABSTRACT Objective To evaluate complication rates of early adjuvant therapy initiation in pediatric patients with endoscopic endonasal resection for skull base tumors. Design Retrospective case series of pediatric patients (0–18 years old) with skull base tumors who underwent endoscopic endonasal resection between 2013 and 2023.
Heta Patel +7 more
wiley +1 more source

