Results 141 to 150 of about 1,352,938 (323)

Steroid Therapy for Bacterial Meningitis [PDF]

, 2017
Routine dexamethasone therapy for bacterial meningitis in pediatric patients is controversial. Two experts debated this topic at the 1993 meeting of the Infectious Diseases Society of America.
Kaplan, Sheldon L., McCracken, George H., Schaad, Urs B.   +2 more
core  

Immune cell infiltration correlates with intestinal permeability, inflammation, and gastrointestinal symptoms in type 1 diabetes

Journal of Diabetes Investigation, EarlyView.
In individuals with type 1 diabetes, immune cell infiltration in the colon mucosa tended to correlate with fecal and systemic markers of intestinal permeability and inflammation, as well as gastrointestinal symptoms. These findings suggest that low‐grade gut immune activation might link the intestinal barrier dysfunction with systemic endotoxin ...
Polina Zalizko, Reinis Isaks, Leonora Pahirko, Aleksejs Fedulovs, Eduards Krustins, Jurijs Nazarovs, Sergejs Dubencovs, Hanne Salmenkari, Markku Lehto, Kaspars Jēkabsons, Una Riekstiņa, Per‐Henrik Groop, Niina Sandholm, Jeļizaveta Sokolovska   +13 more
wiley   +1 more source

Tumor necrosis factor-alpha and interleukin-1 beta levels in children with bacterial, tuberculous and aseptic meningitis

The Turkish Journal of Pediatrics, 1997
Cerebrospinal fluid levels of tumor necrosis factor-alpha and interleukin-1 beta in 78 children with nonbacterial, bacterial and tuberculous meningitis, and in 34 control subjects were analyzed in order to evaluate the involvement of these ...
M Ceyhan, G Kanra, Z Ecevit, G Seçmeer, G Erdem, O Akan, O Müftüoğlu   +6 more
doaj  

Estimation of serum and CSF lactate as a diagnostic and prognostic marker of bacterial and aseptic meningitis in adults: experience from a tertiary care center

MGM Journal of Medical Sciences
Background: Data on the utility of cerebrospinal fluid (CSF) lactate and serum lactate as prognostic markers for bacterial and viral meningitis remain scarce in the Indian setting.
Hasim Reza, Soumyasil Das, Debasish Gond, Linkon Biswas, Subrata Kumar Pal   +4 more
doaj   +1 more source

Primary Amoebic (Naegleria fowleri) Meningoencephalitis Presenting as Status Epilepticus [PDF]

, 2011
Primary amebic meningoencephalitis (PAM) is a rare entity. Usual presenting features are fever, headache and seizures with meningeal signs and this disease carries high mortality rate.
Bharti, V, Gargi, G, Jaret, P, Panda, P, Raina, R, Sharma, A   +5 more
core   +1 more source

The dysregulation of innate immunity by Porphyromonas gingivalis in the etiology of Alzheimer's disease

Journal of Internal Medicine, EarlyView.
Abstract The etiology of Alzheimer's disease (AD) remains under active debate. In this perspective, we explore the hypothesis that a primarily infection‐caused chronic dysregulation and weakening of human innate immunity via the underexpression, degradation, and inactivation of innate immune proteins necessary for direct antimicrobial effects and ...
Annelise E. Barron, Jennifer S. Lin, Mark I. Ryder, Peter Bergman   +3 more
wiley   +1 more source

Antimicrobial Resistance and Infant Mortality in Sri Lanka: A Retrospective Cohort Study

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Objective Sepsis is a major cause of mortality among children, with the highest burden evident in neonates and young infants, particularly, in resource‐constrained healthcare settings. Despite this burden, there are insufficient published data to delineate the epidemiology of neonatal sepsis from many of these settings.
Gayana P. S. Gunaratna, Michelle L. Harrison, Benjamin F. R. Dickson, Rajeev Sathanandaraja, T. M. Ruwanthi Perera, Nambage Shirani Chandrasiri, Anasuya Sutharson, Jannah Baker, Phoebe C. M. Williams   +8 more
wiley   +1 more source

Corrigendum to “Phylogenetic relationships and regional spread of meningococcal strains in the meningitis belt, 2011–2016” EBioMedicine 41 (2019) 488–496

EBioMedicine, 2020
Nadav Topaz, Dominique A. Caugant, Muhamed-Kheir Taha, Ola Brønstad Brynildsrud, Nadia Debech, Eva Hong, Ala-Eddine Deghmane, Rasmata Ouédraogo, Sani Ousmane, Kadidja Gamougame, Berthe-Marie Njanpop-Lafourcade, Seydou Diarra, LeAnne M. Fox, Xin Wang   +13 more
doaj   +1 more source

Incorporating the Competencies of Evidence‐Based Veterinary Medicine Focused on Pharmacotherapeutics Into Clinical Rotations for Small Animal Dermatology and Food Animal Medicine and Surgery at a Veterinary Medical Teaching Hospital in the US

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Building the skills and knowledge necessary to practice evidence‐based veterinary medicine (EBVM) should occur throughout the veterinary curriculum. Operationalizing EBVM includes asking a clinical question in PICO format, searching the biomedical literature for evidence, critically appraising the evidence, and applying the evidence to make a ...
Virginia R. Fajt, Adam P. Patterson, Dusty Nagy, Jennifer Schleining, Kevin Washburn   +4 more
wiley   +1 more source

Photodynamic inactivation increases cell death rate on persistent Staphylococcus aureus

Photochemistry and Photobiology, EarlyView.
Persistent bacteria have the ability to survive extended periods of antibiotic stress by entering a metabolically dormant state. This study investigated persistence formation in two S. aureus strains and evaluated the effects of PDI using curcumin. Post‐PDI time‐kill assays conducted after metabolic recovery showed a higher rate of bacterial death ...
Maria Vitória Silva Pereira, Bruna Carolina Corrêa, Vanderlei Salvador Bagnato, Kate Cristina Blanco   +3 more
wiley   +1 more source