Results 151 to 160 of about 966,118 (275)

Bioengineered Extracellular Vesicles Mitigate Neuroinflammation by Neutralizing Pneumolysin and Delaying Disease Onset in Experimental Pneumococcal Meningitis

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
ABSTRACT Bacterial meningitis is a life‐threatening neurological disorder frequently caused by a Streptococcus pneumoniae (the pneumococcus) infection of the brain. Standard treatment consists of antibiotics to eliminate bacteria and dexamethasone to reduce inflammation.
Kristine Farmen   +9 more
wiley   +1 more source

[In search of strategies for preventing brain damage as a sequela of bacterial meningitis]

open access: yes, 2000
Multiplication of bacteria within the central nervous system compartment triggers a host response with an overshooting inflammatory reaction which leads to brain parenchyma damage.
Täuber, MG, Leib, Stephen L.
core  

Greater Cochlear Damage in Otogenic Versus Meningogenic Meningitis: Hearing Rehabilitation Implications

open access: yesThe Laryngoscope, Volume 136, Issue 9, Page 3998-4005, September 2026.
Otogenic route of meningitis was associated with greater cochlear hair cell loss in comparison with the meningogenic one in this otopathology study. Neuronal depletion has been traditionally implicated in failed hearing rehabilitation of post‐meningitis deafness.
Matheus Pedrosa Tavares   +5 more
wiley   +1 more source

Effect of the Jeffries Simulation Framework on the Core Competence of New Graduate Paediatric Surgery Nurses: A Quasi‐Experimental Study

open access: yesNursing Open, Volume 13, Issue 9, September 2026.
ABSTRACT Aims Newly graduated paediatric surgery nurses must be able to identify and handle potential risks to ensure patient safety. It is necessary to reinforce their understanding of their roles and responsibilities to achieve this goal. However, the limitations of traditional classroom‐based teaching hinder the exploration of learners' potential ...
Wenjing Luo   +3 more
wiley   +1 more source

Clinical Value of Metagenomic Next‐Generation Sequencing Versus Conventional Methods in Diagnosing Cryptococcal Infection After Kidney Transplantation

open access: yesOrgan Medicine, Volume 3, Issue 3, Page 130-138, September 2026.
This retrospective study evaluated metagenomic next‑generation sequencing (mNGS) against conventional methods (India ink, culture, antigen) for diagnosing cryptococcal infection in 16 kidney transplant recipients. mNGS showed a significantly higher positivity rate (93.8% vs 62.5%, p = 0.031) and shorter turnaround time (24 vs. 120 h, p < 0.001).
Luhao Liu   +6 more
wiley   +1 more source

Quaternary structures of Streptococcus pneumoniae nucleoside diphosphate kinase: From hexamers to supramolecular assemblies

open access: yesProtein Science, Volume 35, Issue 9, September 2026.
Abstract The nucleoside diphosphate kinase (NDK) is a key enzyme that controls the balance of nucleotide pools in all living organisms. Beyond this fundamental role, NDKs exert pleiotropic effects in many cellular processes, including cell development, signal transduction, differentiation, tumor metastasis, and gene expression. The quaternary structure
Julie Kerboeuf   +10 more
wiley   +1 more source

Fractal–fractional model for analysis of tuberculosis infection using Ethiopia incidence data

open access: yesQuantitative Biology, Volume 14, Issue 3, September 2026.
Abstract In this study, a fractional‐order SEIuITR $SE{I}_{u}ITR$ model was proposed to examine the transmission of tuberculosis (TB) in the community. The proposed model was rigorously examined for well‐posedness. The basic reproduction number was also derived, and the disease‐free equilibrium was obtained.
Kumama Regassa Cheneke   +2 more
wiley   +1 more source

Use of sterile gowns for single‐shot spinal anaesthesia: consensus guidelines from the Association of Anaesthetists, Royal College of Anaesthetists, Obstetric Anaesthetists' Association, Regional Anaesthesia UK, College of Anaesthesiologists of Ireland and Australian and New Zealand College of Anaesthetists

open access: yesAnaesthesia, Volume 81, Issue 9, Page 1257-1268, September 2026.
Summary Introduction International guideline recommendations vary on the use of sterile gowns during spinal anaesthesia. There is limited evidence of benefit for their routine use and debate about environmental, financial and clinical costs and benefits.
Caroline Phillips   +45 more
wiley   +1 more source

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