Results 141 to 150 of about 966,118 (275)

Subtotal Versus Total Splenectomy in Children With Sickle Cell Disease: Clinical Outcomes and Splenic Function Assessed by Pocked Red Blood Cell Count

American Journal of Hematology, Volume 101, Issue 10, Page 2654-2658, October 2026.
Alma Al Sibaaie, Abdoulaye Sissoko, Carmen Capito, Christophe Chardot, Mariane de Montalembert, Valentine Brousse, Joséphine Brice, Martina Bevacqua, Camille Roussel, Lucie Dumas, Astan Cissé, Pierre Buffet, Slimane Allali   +12 more
wiley   +1 more source

HHV‐6–Positive Meningitis in an Immunocompetent Adult: Diagnostic Challenges in Distinguishing Active Infection From Chromosomal Integration: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Consider human herpesvirus 6 (HHV‐6) in immunocompetent adults with viral meningitis when standard tests are negative. Qualitative CSF PCR requires cautious interpretation because it cannot exclude chromosomally integrated HHV‐6. Serial CSF improvement and rapid clinical recovery may support probable self‐limited infection and help avoid ...
Hatem M. Taha, Anwar Zahran, Orabi Hajjeh, Bara AbuBaha, Mohammed AbuBaha, Omar Marouf   +5 more
wiley   +1 more source

Hydrocephalus and Diffuse Alveolar Hemorrhage as the Initial Manifestation of Systemic Lupus Erythematosus and Antiphospholipid Syndrome: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect many systems, such as the central nervous system (CNS), cardiovascular, musculocutaneous, renal, and respiratory systems, etc. SLE can occur alone or in association with other autoimmune diseases, especially antiphospholipid syndrome (APS).
Ehsan Adib, Narges Gorbanmaleki, Amirreza Eterafi, Sara Jalali Jivan   +3 more
wiley   +1 more source

Prolonged Headache in a 13‐Year‐Old Girl With Acute Lymphoblastic Leukemia: A Case of Possible Neuroinflammatory Complication Responsive to Intravenous Immunoglobulin

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Neurological complications in pediatric acute lymphoblastic leukemia (ALL) may result from disease, CNS involvement, or treatment. We report a 13‐year‐old girl with persistent headache and blurred vision suggestive of raised intracranial pressure.
Amereh Hadizadeh, Hossein Esfahani, Firozeh Hosseini, Afshin Fayyazi, Nasibeh Ghalandari   +4 more
wiley   +1 more source

Concomitant Lemierre's Syndrome and Base‐of‐Skull Osteomyelitis Caused by Arcanobacterium haemolyticum, Complicated by Ceftriaxone‐Associated Cholecystitis: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Lemierre's syndrome and base‐of‐skull osteomyelitis can occur together in immunocompetent adolescents with Arcanobacterium haemolyticum bacteraemia. Prolonged high‐dose ceftriaxone may precipitate symptomatic cholecystitis. Clinicians should consider A.
Angus Lane, Alexandra Stewart
wiley   +1 more source

Clinical decision rules for acute bacterial meningitis: current insights

, 2016
Alain Viallon,1 Elisabeth Botelho-Nevers,2 Fabrice Zeni3 1Emergency Department, 2Department of Infectious Disease, 3Intensive Care Unit, University Hospital, Saint-Etienne, France Abstract: Acute community-acquired bacterial meningitis (BM) requires ...
Viallon A, Zeni F, Botelho-Nevers E
core  

Development and Validation of PubMed and Ovid MEDLINE Search Filters for Exposure Pathways Linking Climate Change With Public Health

Cochrane Evidence Synthesis and Methods, Volume 4, Issue 5, September 2026.
ABSTRACT Introduction Climate change has major health impacts to which researchers and policymakers need to respond. The volume and multidisciplinary nature of climate‐health evidence pose challenges to its comprehensive identification. Search filters are currently not available for this topic.
Maria‐Inti Metzendorf, Ina Monsef, Katherine Jones, L Susan Wieland, Heidrun Janka, Camila Escobar Liquitay, Denise Thomson   +6 more
wiley   +1 more source

Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden

ChemFoodChem, Volume 2, Issue 3, September 2026.
ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley   +1 more source

Pharmacodynamics of antibiotics in experimental bacterial meningitis--two sides to rapid bacterial killing in the cerebrospinal fluid

, 1990
In bacterial meningitis, several pharmacodynamic factors determine therapeutic success--when defined as sterilization of the cerebrospinal fluid (CSF); (i) local host defense deficits require the use of bactericidal antibiotics; (ii) CSF antibiotic ...
Täuber, MG, Sande, MA
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A First‐in‐Japanese Phase 1, Double‐Blind, Placebo‐Controlled, Parallel‐Cohort Study of Sefaxersen, an Antisense Oligonucleotide Targeting Complement Factor B, in Healthy Participants

Clinical Pharmacology in Drug Development, Volume 15, Issue 9, September 2026.
Abstract Increased activity in the complement alternative pathway (AP) plays a key role in diseases such as IgA nephropathy (IgAN). This first‐in‐Japanese double‐blind Phase 1 study investigated the pharmacokinetics (PK), pharmacodynamics (PD), safety, and tolerability of sefaxersen (RO7434656), an antisense oligonucleotide targeting complement factor ...
Takakazu Sato, Hiroyuki Fukase, Takaaki Ishida, Arisa Karasawa   +3 more
wiley   +1 more source