Results 71 to 80 of about 1,314,096 (303)

A Diagnostic Formula for Discrimination of Tuberculous and Bacterial Meningitis Using Clinical and Laboratory Features

Frontiers in Cellular and Infection Microbiology, 2020
Background: The discrimination of tuberculous meningitis and bacterial meningitis remains difficult at present, even with the introduction of advanced diagnostic tools.
Yun Yang, Xin-Hui Qu, Kun-Nan Zhang, Xiao-Mu Wu, Xin-Rong Wang, An Wen, Ling-Juan Li   +6 more
doaj   +1 more source

Frequency of etiological agents of acute bacterial meningitis using culture and polymerase chain reaction assay

New Microbes and New Infections, 2021
Bacterial meningitis is one of the most severe infectious diseases with high rate of morbidity and mortality in developing countries. The current study aimed to investigate the frequency of etiological agents of bacterial meningitis among patients ...
H. Zeighami, S. Roudashti, Sh. Bahari, F. Haghi, N. Hesami   +4 more
doaj   +1 more source

Mechanisms of Brain Injury in Bacterial Meningitis: Workshop Summary [PDF]

, 2017
Morbidity and mortality associated with bacterial meningitis remain high, although antibiotic therapy has improved during recent decades. The major intracranial complications of bacterial meningitis are cerebrovascular arterial and venous involvement ...
Fontana, Adriano, Pfister, Hans-Walter, Scheld, W. Michael, Tomasz, Alexander, Täuber, Martin G.   +4 more
core  

Bacterial outer membrane vesicles and vaccine applications [PDF]

, 2014
Vaccines based on outer membrane vesicles (OMV) were developed more than 20 years ago against Neisseria meningitidis serogroup B. These nano-sized structures exhibit remarkable potential for immunomodulation of immune responses and delivery of “self ...
Acevedo, Reinaldo, Acosta, Armando, Campa, Concepcion, Cardoso, Daniel, Fernandez, Sonsire, Ferro, Valerie, Garcia, Luis, Perez, Jose Luis, Rosenqvist, Einar, Sarmiento, Maria Elena, Zayas, Caridad   +10 more
core   +2 more sources

Bacterial meningitis and tuberculous meningitis. [PDF]

BMJ, 1973
Despite the wide range of antimicrobial drugs available to day the mortality and morbidity from bacterial meningitis is disappointingly high. This disappointment is all the more poignant when one appreciates that some 75% of pyogenic meningitis in Britain results from infection by one of three organisms?namely, Neisseria meningitidis, Streptococcus ...
openaire   +3 more sources

Narsoplimab Results in Excellent Survival in Adults and Children With Hematopoietic Cell Transplant Associated Thrombotic Microangiopathy (TA‐TMA)

American Journal of Hematology, EarlyView.
ABSTRACT Inappropriate complement activation is a key driver of hematopoietic cell transplant‐associated thrombotic microangiopathy (TA‐TMA). Treatment with narsoplimab, an inhibitor of MASP‐2, the effector enzyme of the lectin pathway, resulted in a response rate of 61% in a Phase 2 clinical trial in adults with TA‐TMA.
Michelle L. Schoettler, Sunil Kumar Pusarla, Narinder Nangia, Miguel‐Angel Perales, Rafael F. Duarte, Andreas Grauer, Alessandro Rambaldi   +6 more
wiley   +1 more source

Pediatric Bacterial Meningitis Surveillance in the World Health Organization African Region Using the Invasive Bacterial Vaccine-Preventable Disease Surveillance Network, 2011–2016

Clinical Infectious Diseases, 2019
Background Bacterial meningitis is a major cause of morbidity and mortality in sub-Saharan Africa. We analyzed data from the World Health Organization’s (WHO) Invasive Bacterial Vaccine-preventable Diseases Surveillance Network (2011–2016) to describe ...
J. Mwenda, E. Soda, G. Weldegebriel, R. Katsande, J. Biey, T. Traore, L. De Gouveia, M. du Plessis, A. von Gottberg, M. Antonio, B. Kwambana-Adams, A. Worwui, R. Gierke, Stephanie B. Schwartz, C. V. Van Beneden, A. Cohen, F. Serhan, F. Lessa   +17 more
semanticscholar   +1 more source

Genotype–Phenotype Correlations, Mortality, and Clinical Insights in Keratitis–Ichthyosis–Deafness Syndrome: A Comprehensive Review and Case Report

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Keratosis–ichthyosis–deafness (KID) syndrome is a rare autosomal dominant ectodermal disease caused by mutations in the GJB2 gene, which encodes the gap junction protein Connexin 26 (Cx26) located on Chr. 13q12.11. This study presents the first mortality analysis associated with KID syndrome, focusing on a case report of a Latin American ...
Leslie Patrón‐Romero, Marco Antonio Hernández Lepe, José de Jesús Manríquez Torres, Diego Daniel Aguirre‐Gómez, Natsuo Hayashi‐Mercado, Genaro Rodríguez Uribe, Tadeo Cerón, María Ruiz‐Gamboa, Jesús Alonso Gándara‐Mireles, Ismael Lares‐Asseff, Verónica Loera‐Castañeda, Jorge Alvelais‐Palacios, Lucrecia Arzamendi‐Cepeda, Lidia Magdalena Castañeda‐González, Adolfo García‐Barrón, Francisco Yamal Quiroz Herrera, Francisco González‐Salazar, Horacio Almanza‐Reyes   +17 more
wiley   +1 more source

Phosphatidylcholine PC ae C44:6 in cerebrospinal fluid is a sensitive biomarker for bacterial meningitis

Journal of Translational Medicine, 2020
Background The timely diagnosis of bacterial meningitis is of utmost importance due to the need to institute antibiotic treatment as early as possible.
Leonardo Silva de Araujo, Kevin Pessler, Kurt-Wolfram Sühs, Natalia Novoselova, Frank Klawonn, Maike Kuhn, Volkhard Kaever, Kirsten Müller-Vahl, Corinna Trebst, Thomas Skripuletz, Martin Stangel, Frank Pessler   +11 more
doaj   +1 more source

Genomic dissection of the 1994 Cronobacter sakazakii outbreak in a French neonatal intensive care unit [PDF]

, 2015
Background: Cronobacter sakazakii is a member of the genus Cronobacter that has frequently been isolated from powdered infant formula (PIF) and linked with rare but fatal neonatal infections such as meningitis and necrotising enterocolitis.
Dickins, B, Farbos, A, Forsythe, S, Masood, N, McNally, A, Moore, K, Paszkiewicz, K   +6 more
core   +2 more sources