Results 51 to 60 of about 966,118 (275)

Comparative Analysis of Gram Stain, Culture and Bacterial Antigen Detection in Cerebrospinal Fluid Samples for Laboratory Diagnosis of Acute Bacterial Meningitis in Pediatric Population in A Tertiary Care Hospital [PDF]

, 2023
Acute bacterial meningitis (ABM) is a life threatening infection in children, associated with long term complications and high mortality rate.1,2 Gram staining and culture are routinely used for diagnosis of ABM.
V. Dillirani, K. Chandrasekaran, J. Jayachitra, T. Monisha   +3 more
core   +1 more source

The value of elevated cerebrospinal fluid lactate concentrations in post-neurosurgical bacterial meningitis

BMC Neurology, 2023
Bacterial meningitis is a serious complication after neurosurgery and has a high mortality rate. Early diagnosis and timely treatment are crucial or will have disastrous consequences.
Qin Wang, YongFang Wang, Yan Yang, YanXi Kong, Yuan Peng   +4 more
doaj   +1 more source

Extrapolation and pharmacokinetic protocol design optimization for ceftriaxone as an exemplar for the development of antibiotics for children

British Journal of Clinical Pharmacology, EarlyView.
Aim Ceftriaxone is a cephalosporin commonly used for the treatment of acute, severe infections; however, there are conflicting data on its disposition properties in children, making it a suitable case study for the evaluation of the appropriateness of extrapolation approaches based on exposure matching principles for paediatric patients and exploring ...
Daniel Valente Neves, Umberto Villani, Salvatore D'Agate, Sean Oosterholt, Ricardo de Carvalho Cavalli, Fabio Carmona, Vera Lucia Lanchote, Oscar Della Pasqua   +7 more
wiley   +1 more source

Chiari I Malformation: Review and Update of Current Treatment Options

Clinical Anatomy, EarlyView.
ABSTRACT The pathophysiology of Chiari malformation type I (CM‐I) is complex, involving structural abnormalities at the craniovertebral junction that result in herniation of the cerebellar tonsils through the foramen magnum. In this study, we aim to present and evaluate current treatment options for CM‐I, with a focus on evidence‐based clinical ...
Jordan J. Lo, Shuhei Shiino, Stephen Z. Shapiro, Brianna L. Hines, Noritaka Komune, Carmine Antonio Donofrio, Filippo Badaloni, Antonio Fioravanti, Joseph Lockwood, C. J. Bui, Aaron S. Dumont, R. Shane Tubbs   +11 more
wiley   +1 more source

[Meningitis (II)--acute bacterial meningitis]

, 1999
Acute meningitis is a medical emergency, particularly in patients with rapidly progressing disease, mental status changes or neurological deficits.
Täuber, Martin G., Leib, Stephen L.
core   +1 more source

Comparison of Bordetella species identification among differing rt-PCR assays in the United States

Microbiology Spectrum
In the United States, the general laboratory method for diagnosing pertussis, caused by Bordetella pertussis, is real-time PCR (rt-PCR) targeting insertion sequence 481 (IS481).
Matthew Cole, Ashley K. Simon, Amanda Faulkner, Tami Skoff, Maria L. Tondella, Clemente Montero, Melinda B. Nye, Margaret Williams   +7 more
doaj   +1 more source

Frequency of etiological agents of acute bacterial meningitis using culture and polymerase chain reaction assay

New Microbes and New Infections, 2021
Bacterial meningitis is one of the most severe infectious diseases with high rate of morbidity and mortality in developing countries. The current study aimed to investigate the frequency of etiological agents of bacterial meningitis among patients ...
H. Zeighami, S. Roudashti, Sh. Bahari, F. Haghi, N. Hesami   +4 more
doaj   +1 more source

Bacterial meningitis in Africa

Frontiers in Neurology, 2023
Bacterial meningitis differs globally, and the incidence and case fatality rates vary by region, country, pathogen, and age group; being a life-threatening disease with a high case fatality rate and long-term complications in low-income countries. Africa has the most significant prevalence of bacterial meningitis illness, and the outbreaks typically ...
Tatiana Barichello, Tatiana Barichello, Carlos Henrique Rocha Catalão, Carlos Henrique Rocha Catalão, Ursula K. Rohlwink, Ursula K. Rohlwink, Ursula K. Rohlwink, Martijn van der Kuip, Dan Zaharie, Dan Zaharie, Regan S. Solomons, Ronald van Toorn, Marceline Tutu van Furth, Rodrigo Hasbun, Federico Iovino, Vivian Ssonko Namale, Vivian Ssonko Namale   +16 more
openaire   +3 more sources

Opsoclonus in Pediatric Patients: Differential Diagnosis and a Practical Approach to Evaluation

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Opsoclonus is an ocular dyskinesia characterized by involuntary, arrhythmic, multidirectional saccades. In pediatrics, opsoclonus is most commonly attributed to the rare neuroinflammatory disorder opsoclonus‐myoclonus‐ataxia syndrome (OMAS), typically considered a paraneoplastic syndrome associated with neural crest tumors. However, opsoclonus
Aubrey C. Reed, Supreet S. Randhawa, Jason H. Peragallo, Prabhumallikarjun Patil, Grace Gombolay, Varun Kannan   +5 more
wiley   +1 more source

Analysis of clinical outcomes in pediatric bacterial meningitis focusing on patients without cerebrospinal fluid pleocytosis

, 2017
Background: Cerebrospinal fluid (CSF) cell count and biochemical examinations and cultures form the basis for the diagnosis of bacterial meningitis. However, some patients do not have typical findings and are at a higher risk of being missed or having ...
Lin, Wen-Li;Chi, Hsin;Huang, Fu-Yuan;Huang, Daniel Tsung-Ning;Chiu, Nan-Chang
core   +1 more source