Results 51 to 60 of about 81,624 (225)

Phosphatidylcholine PC ae C44:6 in cerebrospinal fluid is a sensitive biomarker for bacterial meningitis

Journal of Translational Medicine, 2020
Background The timely diagnosis of bacterial meningitis is of utmost importance due to the need to institute antibiotic treatment as early as possible.
Leonardo Silva de Araujo, Kevin Pessler, Kurt-Wolfram Sühs, Natalia Novoselova, Frank Klawonn, Maike Kuhn, Volkhard Kaever, Kirsten Müller-Vahl, Corinna Trebst, Thomas Skripuletz, Martin Stangel, Frank Pessler   +11 more
doaj   +1 more source

Greater Cochlear Damage in Otogenic Versus Meningogenic Meningitis: Hearing Rehabilitation Implications

The Laryngoscope, EarlyView.
Otogenic route of meningitis was associated with greater cochlear hair cell loss in comparison with the meningogenic one in this otopathology study. Neuronal depletion has been traditionally implicated in failed hearing rehabilitation of post‐meningitis deafness.
Matheus Pedrosa Tavares, Henrique Furlan Pauna, Rafael da Costa Monsanto, Nevra Keskin‐Yilmaz, Breno Lima de Almeida, Norma de Oliveira Penido   +5 more
wiley   +1 more source

Unveiling Saint Theobald: A Multidisciplinary Bioanthropological Investigation

International Journal of Osteoarchaeology, EarlyView.
ABSTRACT Saint Theobald of Provins (1033–1066), a French nobleman who embraced voluntary poverty, hermitism, and pilgrimage, represents an early figure in the medieval ascetic movement. He holds historical significance for the diffusion of 11th‐century ascetic ideals, as a hermit saint associated with the Camaldolese order and venerated across northern
Nicola Carrara, Cicero Moraes, Luca Bezzi, Alberto Zanatta, Luca Pagani, Gilberto Artioli, Cinzia Scaggion   +6 more
wiley   +1 more source

RNA sequencing reveals differential long noncoding RNA expression profiles in bacterial and viral meningitis in children

BMC Medical Genomics
Background We aimed to investigate the involvement of long non-coding RNA (lncRNA) in bacterial and viral meningitis in children. Methods The peripheral blood of five bacterial meningitis patients, five viral meningitis samples, and five healthy ...
Xin Li, Suzhen Sun, Huifeng Zhang
doaj   +1 more source

Sequelae due to bacterial meningitis among African children: a systematic literature review

BMC Medicine, 2009
Background African children have some of the highest rates of bacterial meningitis in the world. Bacterial meningitis in Africa is associated with high case fatality and frequent neuropsychological sequelae.
Moïsi Jennifer C, Steinhardt Laura C, Ulland Aaron J, Ramakrishnan Meenakshi, Were Fred, Levine Orin S   +5 more
doaj   +1 more source

The economic burden of RSV-associated illness in children aged < 5 years, South Africa 2011–2016

BMC Medicine, 2023
Background Data on the economic burden of RSV-associated illness will inform decisions on the programmatic implementation of maternal vaccines and monoclonal antibodies.
Jocelyn Moyes, Stefano Tempia, Sibongile Walaza, Meredith L. McMorrow, Florette Treurnicht, Nicole Wolter, Anne von Gottberg, Kathleen Kahn, Adam L. Cohen, Halima Dawood, Ebrahim Variava, Cheryl Cohen   +11 more
doaj   +1 more source

Clinical Value of Metagenomic Next‐Generation Sequencing Versus Conventional Methods in Diagnosing Cryptococcal Infection After Kidney Transplantation

Organ Medicine, EarlyView.
This retrospective study evaluated metagenomic next‑generation sequencing (mNGS) against conventional methods (India ink, culture, antigen) for diagnosing cryptococcal infection in 16 kidney transplant recipients. mNGS showed a significantly higher positivity rate (93.8% vs 62.5%, p = 0.031) and shorter turnaround time (24 vs. 120 h, p < 0.001).
Luhao Liu, Rongxin Chen, Haonan Lin, Yuhe Guo, Guanghui Li, Jiali Fang, Zheng Chen   +6 more
wiley   +1 more source

Role of defensins in immunothrombosis

Rheumatology &Autoimmunity, EarlyView.
Defensins are important proteins that link the immune system and blood clotting, playing a key role in immunothrombosis. α‐defensins mainly come from neutrophils, while β‐defensins are produced by epithelial cells and platelets. These proteins help form blood clots in several ways: they slow down clot breakdown (fibrinolysis), activate platelets, and ...
Yuebing Wang, Guijuan Guo, Xiangjun Liu, Xiaoyu Chen, Wenqiong Wang, Patapong Towiwat, Ru Li, Chun Li   +7 more
wiley   +1 more source

‘Reservoir dogs’: The emerging zoonotic risk associated with European dog imports to the UK

Veterinary Record, EarlyView.
Abstract Background The movement of dogs from continental Europe to the UK poses a growing public health threat due to the associated risk of disease incursions. Current legislation is insufficient to address the risks and pre‐import control measures are focused only on rabies virus and the fox tapeworm Echinococcus multilocularis. Methods We conducted
Poppy Simonson, Tapan Bhattacharyya, Michael A. Miles   +2 more
wiley   +1 more source

Epidemiological characteristics and disease burden of bacterial meningitis in hospitalized children in China: a 6-year nationwide retrospective study

BMC Infectious Diseases
Bacterial meningitis is a severe infectious disease. Study of bacterial meningitis of children in recent years are limited. It is unclear whether there have been any changes in the epidemiological characteristics of bacterial meningitis during the years ...
Linlin Liu, Xinyu Wang, Lingyun Guo, Tianming Chen, Bing Hu, Binglin Jian, Guoshuang Feng, Yueping Zeng, Gang Liu   +8 more
doaj   +1 more source